在人类体外受精项目中使用小鼠植入前胚胎进行培养试剂的质量控制：一则警示
The use of mouse preimplantation embryos for quality control of culture reagents in human in vitro fertilization programs: a cautionary note.
作者信息
Fleming T P, Pratt H P, Braude P R
出版信息
Fertil Steril. 1987 May;47(5):858-60. doi: 10.1016/s0015-0282(16)59179-1.
PMID:3569563
Abstract
Mouse embryos with their zonae pellucidae intact are more resistant to suboptimal culture conditions than are zona-free embryos. This observation questions the general practice of using zona-intact preimplantation mouse embryos to monitor the quality of media and reagents used in human IVF programs.
摘要
带有完整透明带的小鼠胚胎比无透明带胚胎对次优培养条件更具抵抗力。这一观察结果对使用带有完整透明带的植入前小鼠胚胎来监测人类体外受精程序中所用培养基和试剂质量的常规做法提出了质疑。
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