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基于分子间π-π相互作用通过物理交联制备温度响应性聚合物凝胶。

Development of temperature-responsive polymeric gels with physical crosslinking due to intermolecular 𝜋-𝜋 interactions.

作者信息

Shah Rishabh A, Runge Tyler, Ostertag Thomas W, Tang Shuo, Dziubla Thomas D, Hilt J Zach

机构信息

Superfund Research Center, University of Kentucky, Lexington, KY 40536, USA.

Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY 40506, USA.

出版信息

Polym Int. 2022 Mar;71(3):292-300. doi: 10.1002/pi.6328. Epub 2021 Nov 19.

DOI:10.1002/pi.6328
PMID:35695835
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9173683/
Abstract

Poly(N-isopropylacrylamide) PNIPAAm was polymerized with co-monomers containing a biphenyl moiety to create a unique thermoresponsive physically crosslinked system due to the presence of pi-pi interactions between the biphenyl moieties. The biphenyl monomers used were 2-phenylphenol monoacrylate (2PPMA) and 4-phenylphenol monoacrylate (4PPMA). These monomers were utilized to synthesize a set of polymers with biphenyl monomer (2PPMA/4PPMA) content from 2.5 to 7.5 mole percent and with initiator concentrations from 0.1 and 1.0 weight percent. The resulting polymers were characterized by various techniques, such as gel permeation chromatography (GPC), swelling studies and mechanical testing. The decrease in the average molecular weight of the polymers due to the increase in the concentration of initiator was confirmed by GPC results. Swelling studies confirmed the expected temperature dependent swelling properties and explored the impact of the biphenyl comonomers. These studies indicated that with the increase in biphenyl comonomers, the physical crosslinking increases which leads to decrease in the swelling ratio. The results from the mechanical tests also depict the effect of the concentration of biphenyl comonomers. These physically crosslinked polymeric systems with their unique properties have potential applications spanning environmental remediation/sensing, biomedicine, etc.

摘要

聚（N-异丙基丙烯酰胺）（PNIPAAm）与含有联苯部分的共聚单体聚合，由于联苯部分之间存在π-π相互作用，从而形成了一种独特的热响应物理交联体系。所使用的联苯单体为2-苯基苯酚单丙烯酸酯（2PPMA）和4-苯基苯酚单丙烯酸酯（4PPMA）。这些单体被用于合成一组联苯单体（2PPMA/4PPMA）含量为2.5至7.5摩尔百分比且引发剂浓度为0.1至1.0重量百分比的聚合物。通过凝胶渗透色谱法（GPC）、溶胀研究和力学测试等各种技术对所得聚合物进行了表征。GPC结果证实了由于引发剂浓度增加导致聚合物平均分子量降低。溶胀研究证实了预期的温度依赖性溶胀特性，并探究了联苯共聚单体的影响。这些研究表明，随着联苯共聚单体的增加，物理交联增加，导致溶胀率降低。力学测试结果也描述了联苯共聚单体浓度的影响。这些具有独特性能的物理交联聚合物体系在环境修复/传感、生物医学等领域具有潜在应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3feb/9173683/6f102babc7c6/nihms-1758209-f0008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3feb/9173683/ec66f922ab48/nihms-1758209-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3feb/9173683/c17744e03a81/nihms-1758209-f0002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3feb/9173683/75049efc49a7/nihms-1758209-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3feb/9173683/bca8d769c08e/nihms-1758209-f0006.jpg
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3
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