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新老年脱水筛查工具的敏感性和特异性:一项观察性诊断研究。

Sensitivity and specificity of the new Geriatric Dehydration Screening Tool: An observational diagnostic study.

机构信息

Healthcare Professions Department, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

Department of Clinical Sciences and Community Health, Laboratory G.A. Maccacaro, University of Milan, Milan, Italy.

出版信息

Nutrition. 2022 Sep;101:111695. doi: 10.1016/j.nut.2022.111695. Epub 2022 Apr 22.

Abstract

OBJECTIVES

The aim of this study was to evaluate the diagnostic accuracy of the Geriatric Dehydration Screening Tool-Modified (GDST-M) in detecting dehydration in older people and, if possible, to simplify the tool and make it easier to use.

METHODS

This was a monocentric diagnostic accuracy study. We involved people ≥65 y of age with a Mini Mental State Evaluation (MMSE) score >24 and who were hospitalized in five medical wards of a large teaching hospital in Milan (Italy). We administered the GDST-M to hospitalized older people who met the inclusion criteria and compared outcomes with the values of serum osmolarity to evaluate their dehydration status and the accuracy of the tool.

RESULTS

A total of 299 older people were recruited, of which 202 were dehydrated and 97 were hydrated. The GDST-M, with a cutoff value of 6, showed a sensitivity of 61.9% and a specificity of 47.2%. Multiple correspondence analysis and cluster analysis enabled extraction of 9 items from the 23 items present in the GDST-M. The new tool had a moderate diagnostic accuracy in detecting dehydration in older people aged over 75 y, with a sensitivity of 63.4% and a specificity of 69.6%.

CONCLUSIONS

The short form of the tool is simple and contains minimally invasive assessments of low fluid intake dehydration in older people. The new GDST could also be easily used by lay people after a short training session.

摘要

目的

本研究旨在评估改良老年脱水筛查工具(GDST-M)诊断老年人脱水的准确性,并尽可能简化该工具,使其更易于使用。

方法

这是一项单中心诊断准确性研究。我们纳入了年龄≥65 岁、Mini 精神状态评估(MMSE)评分>24 分且在意大利米兰一所大型教学医院的 5 个内科病房住院的患者。我们对符合纳入标准的住院老年人进行 GDST-M 评估,并将结果与血清渗透压值进行比较,以评估其脱水状态和工具的准确性。

结果

共纳入 299 名老年人,其中 202 名脱水,97 名未脱水。GDST-M 的截断值为 6 时,其敏感性为 61.9%,特异性为 47.2%。多元对应分析和聚类分析从 GDST-M 中的 23 个项目中提取了 9 个项目。新工具对检测 75 岁以上老年人脱水具有中等诊断准确性,敏感性为 63.4%,特异性为 69.6%。

结论

该工具的简短形式简单,包含对老年人低液体摄入脱水的微创评估。经过短期培训,新的 GDST 也可以由非专业人员轻松使用。

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