Fléjou J F, Degott C, Kharsa G, Soulier A, Rueff B, Potet F
Gastroenterol Clin Biol. 1987 Feb;11(2):165-8.
Alcoholic foamy degeneration is a recently recognized type of alcohol related liver disease. We report 3 cases occurring in men aged 40, 51 and 38 years. All 3 patients had marked elevation of serum aminotransferases which decreased rapidly after withdrawal of alcohol intake. In each case, the diagnosis of alcoholic foamy degeneration was made on microscopic examination of a liver specimen. The lesion is similar to that found in other diseases in which microvesicular steatosis is a main finding, such as acute fatty liver of pregnancy and Reye's syndrome. This condition, when isolated, is a rare form of alcoholic liver disease. A milder form probably exists, more commonly associated with other alcoholic liver injuries. The diagnosis of alcoholic foamy degeneration must be suspected when marked elevation of serum aminotransferases is observed in alcoholic patients, and it must be confirmed by microscopic examination.
酒精性泡沫样变性是一种最近才被认识的酒精相关性肝病类型。我们报告了3例分别发生于40岁、51岁和38岁男性的病例。所有3例患者血清转氨酶均显著升高，在戒酒之后迅速下降。每例均通过肝脏标本的显微镜检查确诊为酒精性泡沫样变性。该病变与其他以微泡性脂肪变性为主要表现的疾病（如妊娠急性脂肪肝和瑞氏综合征）中所见的病变相似。这种情况若单独出现，则是酒精性肝病的一种罕见形式。可能存在一种较轻的形式，更常与其他酒精性肝损伤相关。当在酒精性患者中观察到血清转氨酶显著升高时，必须怀疑酒精性泡沫样变性的诊断，且必须通过显微镜检查来确诊。
