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红外线过滤窗膜预防常规光疗新生儿高胆红素血症中高热的疗效:一项随机对照试验。

The efficacy of infrared filter window film to prevent hyperthermia in neonatal hyperbilirubinemia with conventional phototherapy: a randomized control trial.

机构信息

Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Thailand.

Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Thailand.

出版信息

Pediatr Neonatol. 2022 Sep;63(5):489-495. doi: 10.1016/j.pedneo.2021.12.014. Epub 2022 May 27.

Abstract

BACKGROUND

Phototherapy is the first-line treatment of neonatal hyperbilirubinemia. Possible side effects caused by phototherapy include hyperthermia and dehydration. Currently, there are many types of infrared blocking film for potential use in reducing infrared radiation exposure and preventing hyperthermia. This study aims to evaluate the efficacy of infrared blocking film in preventing hyperthermia during the first 24 h of phototherapy.

METHODS

The randomized controlled trial study was carried out in 44 newborns with hyperbilirubinemia. Infrared filter film with 75% visible light transmission and 90% infrared rejection was used in the study. Body temperature was measured for the assessment of the efficacy of filter film from axillary and rectal routes.

RESULTS

There was a significantly lower incidence of hyperthermia from the axillary temperature in the group with infrared blocking film compared to the control group (p = 0.031). The axillary temperature between before and after initiation of phototherapy in filter film group was significantly better (p = 0.008). According to efficacy of treatment, the study demonstrated that infrared filter film did not interfere with the efficacy of phototherapy in reducing bilirubin level.

CONCLUSIONS

The infrared filter film was significantly more effective in preventing hyperthermia from phototherapy in the first 24 h without causing any significant difference in reduction of bilirubin level.

THAI CLINICAL TRIALS REGISTRY

TCTR20190619001.

摘要

背景

光疗是新生儿高胆红素血症的一线治疗方法。光疗可能引起的副作用包括发热和脱水。目前,有许多种红外线阻隔膜可用于减少红外线辐射暴露并预防发热。本研究旨在评估红外线阻隔膜在预防光疗最初 24 小时内发热的疗效。

方法

本随机对照试验研究纳入了 44 例高胆红素血症新生儿。研究中使用了可见光透过率为 75%、红外线阻隔率为 90%的红外线滤光片。通过腋温测量评估滤光片的疗效。

结果

与对照组相比,使用红外线阻隔膜的组腋温发热的发生率显著降低(p = 0.031)。滤光片组在开始光疗前后的腋温差异有统计学意义(p = 0.008)。根据治疗效果,研究表明红外线滤光片不会干扰光疗降低胆红素水平的疗效。

结论

在最初 24 小时内,红外线滤光片在预防光疗引起的发热方面明显更有效,而对胆红素水平的降低没有造成任何显著差异。

泰国临床试验注册中心

TCTR20190619001。

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