无机多聚磷酸盐在线粒体能量代谢和病理学中的作用。
Inorganic Polyphosphate in Mitochondrial Energy Metabolism and Pathology.
机构信息
Department of Molecular Pathobiology, New York University, New York, NY, USA.
出版信息
Prog Mol Subcell Biol. 2022;61:15-26. doi: 10.1007/978-3-031-01237-2_2.
PMID:35697935
Abstract
In this chapter, the current understanding of the potential roles played by polyphosphate in mitochondrial function with a specific focus on energy metabolism and mitochondrial pathologies caused by stress is summarized. Here we will discuss details of the possible ion transporting mechanisms of mitochondria that might involve polyP and their role in mitochondrial physiology and pathology are discussed.
摘要
在本章中，总结了目前对多聚磷酸盐在线粒体功能中可能发挥的作用的理解，特别关注能量代谢和应激引起的线粒体病变。在这里，我们将讨论可能涉及多聚磷酸盐的线粒体的可能离子转运机制的细节，并讨论它们在线粒体生理学和病理学中的作用。
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