Department of Rehabilitation Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.
Department of Rehabilitation Medicine, Tokyo Bay Rehabilitation Hospital, 4-1-1, Yatsu, Narashino City, Chiba, 275-0026, Japan.
BMC Neurol. 2022 Jun 13;22(1):219. doi: 10.1186/s12883-022-02745-8.
To investigate the cognitive function and its relation to the home discharge of patients following subacute stroke.
This retrospective cohort study included 1,229 convalescent patients experiencing their first subacute stroke. We determined discharge destination and demographic and clinical information. We recorded the following measurement scores: Mini-Mental State Examination (MMSE) score, Stroke Impairment Assessment Set score, grip strength, and Functional Independence Measure (FIM). We performed a multivariable logistic regression analysis with the forced-entry method to identify factors related to home discharge.
Of the 1,229 participants (mean age: 68.7 ± 13.5 years), 501 (40.8%), 735 (59.8%), and 1,011 (82.3%) were female, had cerebral infarction, and were home discharged, respectively. Multivariable logistic regression analysis revealed that age (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.91 - 0.96; P < 0.001), duration from stroke onset to admission (OR, 0.98; 95% CI, 0.96 - 0.99; P = 0.003), living situation (OR, 4.40; 95% CI, 2.69 - 7.20; P < 0.001), MMSE score at admission (OR, 1.05; 95% CI, 1.00 - 1.09; P = 0.035), FIM motor score at admission (OR, 1.04; 95% CI, 1.01 - 1.06; P = 0.001), and FIM cognitive score at admission (OR, 1.08; 95% CI, 1.04 - 1.13; P < 0.001) were significantly associated with home discharge.
MMSE at admission is significantly associated with home discharge in patients with subacute stroke.
探讨亚急性脑卒中患者认知功能与其出院去向的关系。
本回顾性队列研究纳入了 1229 例首次发生亚急性脑卒中的恢复期患者。我们确定了出院去向和人口统计学及临床信息。我们记录了以下测量评分：简易精神状态检查（MMSE）评分、脑卒中损伤评估量表评分、握力和功能独立性测量（FIM）。我们采用强制进入法进行多变量逻辑回归分析，以确定与家庭出院相关的因素。
在 1229 名参与者中（平均年龄：68.7±13.5 岁），501 名（40.8%）、735 名（59.8%）和 1011 名（82.3%）分别为女性、脑梗死和家庭出院。多变量逻辑回归分析显示，年龄（比值比 [OR]，0.93；95%置信区间 [CI]，0.91-0.96；P<0.001）、脑卒中发病至入院时间（OR，0.98；95% CI，0.96-0.99；P=0.003）、居住状况（OR，4.40；95% CI，2.69-7.20；P<0.001）、入院时 MMSE 评分（OR，1.05；95% CI，1.00-1.09；P=0.035）、入院时 FIM 运动评分（OR，1.04；95% CI，1.01-1.06；P=0.001）和入院时 FIM 认知评分（OR，1.08；95% CI，1.04-1.13；P<0.001）与家庭出院显著相关。
入院时的 MMSE 与亚急性脑卒中患者的家庭出院显著相关。
