Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou City, 450052, Henan Province, China.
J Cardiothorac Surg. 2022 Jun 13;17(1):153. doi: 10.1186/s13019-022-01883-x.
To evaluate the clinical results of the vacuum sealing drainage (VSD) combined with a naso-intestinal nutritional tube (NIT) and a gastric decompression tube (GDT) for the treatment of esophagogastrostomy neck fistula (ENF).
From January 2018 to October 2020, twenty patients (13 men and 7 women, ages 46-72) with ENF secondary to esophagogastrostomy were treated with VSD combined with NIT and GDT. Technical and clinical success rates, the incidence of early/late complications, the time of fistula closure (TFC) and therapy-related indicators were analyzed. The Karnofsky score and Eastern Cooperative Oncology Group (ECOG) score were compared before and after triple treatment.
Technical and clinical success rates were 100% and 85%, respectively. Early complications occurred in 5/20 (25%) patients, and late complications occurred in 8/20 (40%) patients. The median TFC was 18 days (range 10-23). All therapy-related indicators were normalized posttreatment. The Karnofsky score and ECOG score after treatment were significantly different compared with pretreatment scores (p < 0.001).
VSD combined with NIT and GDT is a safe and effective strategy for ENF, while severe strictures warrant further research.
评估真空密封引流(VSD)联合鼻肠营养管(NIT)和胃减压管(GDT)治疗食管胃吻合口瘘(ENF)的临床效果。
自 2018 年 1 月至 2020 年 10 月,20 例因食管胃吻合术后发生 ENF 的患者(男 13 例,女 7 例,年龄 46-72 岁)接受了 VSD 联合 NIT 和 GDT 治疗。分析技术和临床成功率、早期/晚期并发症发生率、瘘口关闭时间(TFC)和治疗相关指标。比较三重治疗前后卡诺夫斯基评分和东部合作肿瘤学组(ECOG)评分。
技术和临床成功率分别为 100%和 85%。5/20(25%)例患者出现早期并发症,8/20(40%)例患者出现晚期并发症。中位 TFC 为 18 天(范围 10-23)。所有治疗相关指标治疗后均恢复正常。治疗后的卡诺夫斯基评分和 ECOG 评分与治疗前的评分有显著差异(p<0.001)。
VSD 联合 NIT 和 GDT 是治疗 ENF 的一种安全有效的策略,而严重狭窄则需要进一步研究。