Randall Children's Hospital at Legacy Emanuel Medical Center, Portland, OR, USA.
Biostatistics Core of Children's Hospital Colorado Research Institute, University of Colorado School of Medicine, Aurora, CO, USA.
Dis Esophagus. 2021 Oct 11;34(10). doi: 10.1093/dote/doab029.
Esophageal food impactions (EFI) are associated with esophageal pathology, most commonly eosinophilic esophagitis (EoE). Obtaining biopsies provides opportunity for diagnosis, which is important since treatment of EoE decreases the risk for future EFI. Outpatient follow-up rates remain suboptimal and outcomes of patients without timely follow-up are unknown. We aimed to identify the factors associated with pediatric subspecialty follow-up post-EFI and to determine the symptom burden in patients without follow-up. We performed a retrospective review of patients presenting with EFI at a tertiary children's hospital between 2010 and 2018. Patients without subspecialty follow-up within 1 year of EFI were included in a prospective telephone survey investigating the barriers to care, outcomes, and symptoms. Clinical characteristics were compared between groups. Multivariate analysis was used to control for multiple variables. There were 127 EFI identified in 123 individuals (73% male, mean age: 12.2 years). Esophageal biopsies were collected in 76% of cases, and 49% of patients had follow-up. Individuals with follow-up were more likely (P ≤ 0.05) to have had biopsies. In a multivariate analysis, written recommendation for follow-up (Odds Ratio: 6.9 [2.4-19.5], P = 0.001) as well as atopic history and identified stricture were associated with a higher likelihood of follow-up. Those without follow-up had subsequent stricture (35%), dilation (44%), or EFI (39%), and 55% (12/22) described ongoing esophageal symptoms. Identification of treatable findings at time of EFI and ongoing symptom burden after EFI support an imperative for follow-up after EFI. Clear recommendations are a modifiable factor that may improve follow-up in this population.
食管食物嵌塞(EFI)与食管病理学有关,最常见的是嗜酸性食管炎(EoE)。获取活检提供了诊断的机会,这很重要,因为 EoE 的治疗可以降低未来发生 EFI 的风险。门诊随访率仍然不理想,并且没有及时随访的患者的结局尚不清楚。我们旨在确定与 EFI 后儿科专科随访相关的因素,并确定未随访患者的症状负担。我们对 2010 年至 2018 年在一家三级儿童医院就诊的 EFI 患者进行了回顾性研究。在 EFI 后 1 年内没有接受专科随访的患者,我们进行了一项前瞻性电话调查,调查了护理障碍、结局和症状。比较了两组的临床特征。使用多变量分析来控制多个变量。在 123 名患者中发现了 127 例 EFI(73%为男性,平均年龄:12.2 岁)。在 76%的病例中收集了食管活检,49%的患者有随访。有随访的患者更有可能(P≤0.05)进行了活检。在多变量分析中,书面随访建议(优势比:6.9 [2.4-19.5],P=0.001)以及特应性病史和发现的狭窄与更高的随访可能性相关。没有随访的患者随后发生了狭窄(35%)、扩张(44%)或 EFI(39%),并且 55%(12/22)的患者描述了持续的食管症状。在 EFI 时发现可治疗的发现以及 EFI 后持续的症状负担支持 EFI 后随访的必要性。明确的建议是可改变的因素,可以改善该人群的随访。