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一名复发性急性淋巴细胞白血病成人患者的急性单侧前房积脓性葡萄膜炎和继发性青光眼

Acute Unilateral Hypopyon Uveitis and Secondary Glaucoma in an Adult With Relapsing Acute Lymphoblastic Leukemia.

作者信息

Thulasidas Mithun, Patyal Sagarika

机构信息

Glaucoma, Centre for Sight, New Delhi, IND.

Glaucoma, Centre For Sight, New Delhi, IND.

出版信息

Cureus. 2022 May 13;14(5):e24968. doi: 10.7759/cureus.24968. eCollection 2022 May.

DOI:10.7759/cureus.24968
PMID:35698696
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9188782/
Abstract

Anterior segment infiltration in acute lymphoblastic leukemia (ALL) presenting as hypopyon uveitis in an adult is rare. We report this case as an uncommon presentation in a patient in remission after chemotherapy for ALL. In addition to the hypopyon, the patient presented with congested eye caused by secondary raised intraocular pressure. There is a need to maintain a high index of clinical suspicion in uveitis cases, as early diagnosis of ocular malignancy can save vision. Atypical unilateral hypopyon, even in adults, can be an indication of relapsing ALL.

摘要

急性淋巴细胞白血病（ALL）在成人中表现为前房积脓性葡萄膜炎的前段浸润很少见。我们报告此病例，为ALL化疗后缓解期患者的一种罕见表现。除了前房积脓外，该患者还因继发性眼压升高出现眼部充血。在葡萄膜炎病例中需要保持高度的临床怀疑，因为眼部恶性肿瘤的早期诊断可以挽救视力。非典型的单侧前房积脓，即使在成人中，也可能是ALL复发的迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/905a/9188782/f8117540ee7d/cureus-0014-00000024968-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/905a/9188782/a430f77c4a09/cureus-0014-00000024968-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/905a/9188782/f8117540ee7d/cureus-0014-00000024968-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/905a/9188782/a430f77c4a09/cureus-0014-00000024968-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/905a/9188782/f8117540ee7d/cureus-0014-00000024968-i02.jpg

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Ophthalmologic manifestations as the initial presentation of chronic myeloid leukemia: A review.眼科表现作为慢性髓细胞白血病的首发表现：综述。
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Relapsing acute myeloid leukemia presenting as hypopyon uveitis.复发性急性髓系白血病表现为前房积脓性葡萄膜炎。
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Am J Ophthalmol. 2005 Apr;139(4):719-21. doi: 10.1016/j.ajo.2004.09.074.
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Variations in the presentation of primary intraocular lymphoma: case reports and a review.原发性眼内淋巴瘤临床表现的变异：病例报告及文献综述
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Uveitis masquerade syndromes.葡萄膜炎伪装综合征
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