Department of Ophthalmology, Jaslok Hospital and Research Centre, Dr. G. Deshmukh Marg, Mumbai 400 026, India.
Indian J Ophthalmol. 2011 Sep-Oct;59(5):391-3. doi: 10.4103/0301-4738.83621.
Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with "red eye" caused by ocular surface disease due to concurrent graft-versus-host disease and glaucoma. The classical manifestations of masquerade syndrome due to AML were altered by concurrent pathologies. Media opacities further confounded the differential diagnosis. We highlight the investigations used to arrive at a definitive diagnosis. In uveitis, there is a need to maintain a high index of clinical suspicion, as early diagnosis in ocular malignancy can save sight and life.
前节浸润在急性髓系白血病(AML)表现为前房积脓性葡萄膜炎是非常罕见的。我们报告了这例患者,在 AML 骨髓移植缓解后,出现了这种不常见的表现。除了前房积脓外,由于移植物抗宿主病和青光眼并发,该患者还出现了“红眼病”,这是由眼表疾病引起的。由于 AML 引起的伪装综合征的典型表现被并发的病理改变所改变。眼部混浊进一步混淆了鉴别诊断。我们强调了用于明确诊断的检查。在葡萄膜炎中,需要保持高度的临床怀疑指数,因为眼部恶性肿瘤的早期诊断可以挽救视力和生命。