[Analysis of hypotheses and simulation of selection for a suppressor affecting the manifestations of the fused gene in mice].

The t12 haplotype decreases sharply manifestation of fused gene in mice. The selection for increasing the penetrance of fused gene was made in Fu/t12 stock. The different computer models of selection process were compared. The hypothesis giving the best coincidence with experimental data supposes the presence of a semidominant gene suppressing the effect of t12 on Fu gene in chromosome 8.