Harris Andrew J, Foley Nicole M, Williams Tiffani L, Murphy William J
Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, USA.
Interdisciplinary Program in Genetics & Genomics, Texas A&M University, College Station, TX, USA.
Mol Biol Evol. 2022 Jun 14;39(6). doi: 10.1093/molbev/msac130.
Tree House Explorer (THEx) is a genome browser that integrates phylogenomic data and genomic annotations into a single interactive platform for combined analysis. THEx allows users to visualize genome-wide variation in evolutionary histories and genetic divergence on a chromosome-by-chromosome basis, with continuous sliding window comparisons to gene annotations (GFF/GTF), recombination rates, and other user-specified, highly customizable feature annotations. THEx provides a new platform for interactive phylogenomic data visualization to analyze and interpret the diverse evolutionary histories woven throughout genomes. Hosted on Conda, THEx integrates seamlessly into new or pre-existing workflows.
树屋浏览器(THEx)是一款基因组浏览器,它将系统发育基因组数据和基因组注释整合到一个单一的交互式平台中,用于联合分析。THEx允许用户在逐个染色体的基础上可视化进化历史中的全基因组变异以及遗传差异,并与基因注释(GFF/GTF)、重组率和其他用户指定的、高度可定制的特征注释进行连续滑动窗口比较。THEx为交互式系统发育基因组数据可视化提供了一个新平台,以分析和解释贯穿整个基因组的多样进化历史。THEx托管在Conda上,可无缝集成到新的或现有的工作流程中。