Fernández-Ruiz J J, Ubeda E, Cebeira M, Agrasal C, Tresguerres J A, Ramos J A, Esquifino A I
Horm Res. 1987;25(2):105-12. doi: 10.1159/000180640.
In order to study the possible role on prolactin secretion of the catecholamines present in ectopic pituitaries, female rats bearing an anterior pituitary graft under the kidney capsule since day 30 of life and their sham-operated controls, were sacrificed at 1, 2, 4, 7, 15, 30, 45 and 60 days after the operation. Data obtained showed a significant increase in plasma prolactin levels in grafted rats versus controls from the 4th day on after the grafting (p less than 0.01) until the 60th day (p less than 0.001). Dopamine content in the ectopic pituitary of grafted rats was higher than in their own in situ pituitaries or on those of sham-operated rats until day 45 being similar to them afterwards. Norepinephrine was also present in the pituitary graft but was not detected in the in situ pituitaries. The grafting of an anterior pituitary gland in an ectopic location was able to induce changes in the local catecholaminergic control of the prolactin secretion.
为了研究异位垂体中儿茶酚胺对催乳素分泌可能产生的作用，从出生第30天起就在肾包膜下移植了垂体前叶的雌性大鼠及其假手术对照组，在术后1、2、4、7、15、30、45和60天处死。所获得的数据表明，移植大鼠的血浆催乳素水平自移植后第4天起（p小于0.01）至第60天（p小于0.001）与对照组相比有显著升高。移植大鼠异位垂体中的多巴胺含量在第45天之前高于其自身原位垂体或假手术大鼠的垂体，之后则与它们相似。去甲肾上腺素也存在于垂体移植组织中，但在原位垂体中未检测到。将垂体前叶移植到异位位置能够诱导催乳素分泌的局部儿茶酚胺能控制发生变化。
