Xu Zhiwei, Qian Long, Zhang Lijuan, Gao Yang, Huang Su
Department of Cardiac Surgery, Huai'an First People's Hospital, The Affiliated Huai'an No. 1 People's Hospital of Nanjing Medical University Huai'an, Jiangsu Province, China.
Am J Transl Res. 2022 May 15;14(5):3481-3487. eCollection 2022.
To investigate the predictive value of N-terminal pro brain natriuretic peptide (NT-proBNP), procalcitonin and central venous pressure (CVP) for new atrial fibrillation after cardiac surgery.
Patients underwent cardiac surgery in Huai'an First People's Hospital from June 2019 to December 2020 were enrolled in this study. Patients without POAF after surgery were included in the control group, and patients with POAF after surgery were included in the POAF group. Clinical data of patients were collected and retrospectively analyzed.
The incidence of in-hospital complications, length of stay and cost of hospitalization in the POAF group were significantly higher than those in the control group; Moreover, there were significant differences in central venous pressure, peak cTnI, NT-proBNP, procalcitonin, and white blood cell counts between the two groups. NT-proBNP, procalcitonin and elevated central venous pressure are independent risk factors for POAF in patients after cardiac surgery.
NT-proBNP, procalcitonin and CVP were closely related with atrial fibrillation after cardiac surgery. The combination of NT-proBNP, procalcitonin and CVP had a better discriminative ability for new atrial fibrillation after cardiac surgery compared to either of them alone.
探讨N末端脑钠肽前体（NT-proBNP）、降钙素原及中心静脉压（CVP）对心脏手术后新发心房颤动的预测价值。
选取2019年6月至2020年12月在淮安市第一人民医院行心脏手术的患者纳入本研究。术后无阵发性房颤（POAF）的患者纳入对照组，术后发生POAF的患者纳入POAF组。收集患者临床资料并进行回顾性分析。
POAF组患者的院内并发症发生率、住院时间及住院费用均显著高于对照组；此外，两组患者的中心静脉压、肌钙蛋白I峰值、NT-proBNP、降钙素原及白细胞计数存在显著差异。NT-proBNP、降钙素原及中心静脉压升高是心脏手术后患者发生POAF的独立危险因素。
NT-proBNP、降钙素原及CVP与心脏手术后心房颤动密切相关。与单独使用NT-proBNP、降钙素原或CVP相比，三者联合对心脏手术后新发心房颤动具有更好的鉴别能力。
