Wael Mohamed Mohamed, Althahabi Rawan, Abubaker Faisal, Sharif Omar
Department of Internal Medicine, King Hamad University Hospital, Al-Muharraq, Bahrain.
Department of Gastroenterology, Hepatology and Endoscopy, King Hamad University Hospital, Al-Muharraq, Bahrain.
Case Rep Gastroenterol. 2022 Apr 21;16(1):264-269. doi: 10.1159/000524192. eCollection 2022 Jan-Apr.
Pseudomelanosis of the upper gastrointestinal tract is a rare diagnosis of undetermined significance, most commonly affecting the duodenum. Endoscopically, it is characterized by dark spickled pigmentation . Its development has been linked to certain conditions and medications. Involvement of the stomach is extremely rare with very few cases reported in the literature to date. We report an 85-year-old male who is known to have type 2 diabetes mellitus, dyslipidemia, iron deficiency anemia, and chronic kidney disease who underwent an esophagogastroduodenoscopy for evaluation of upper gastrointestinal bleeding and was found to have gastric and duodenal pseudomelanosis confirmed by biopsy. It is an extremely rare benign condition, but metastatic melanoma has to be ruled out, as was done in this case.
上消化道假黑色素沉着症是一种意义未明的罕见诊断，最常累及十二指肠。在内镜检查中，其特征为深色斑点状色素沉着。其发生与某些疾病和药物有关。胃受累极为罕见，迄今为止文献报道的病例极少。我们报告一例85岁男性，已知患有2型糖尿病、血脂异常、缺铁性贫血和慢性肾脏病，因上消化道出血接受了食管胃十二指肠镜检查，活检证实患有胃和十二指肠假黑色素沉着症。这是一种极其罕见的良性疾病，但必须排除转移性黑色素瘤，本病例即如此。
