Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
J Appl Clin Med Phys. 2022 Aug;23(8):e13668. doi: 10.1002/acm2.13668. Epub 2022 Jun 15.
The aim was to compare Smart Segmentation of Eclipse treatment planning system and Atlas Segment of MIM software for liver delineation for resin yttrium-90 (Y-90) procedures.
CT images of 20 patients treated with resin Y-90 selective internal radiation therapy (SIRT) were tested. Liver contours generated with Smart Segmentation and Atlas Segment were compared with physician manually delineated contours. Dice similarity coefficient (DSC), mean distance to agreement (MDA), and ratio of volume (RV) were calculated. The contours were evaluated with activity calculations and ratio of activity (RA) was calculated.
Mean DSCs were 0.77 and 0.83, MDAs were 0.88 and 0.71 cm, mean RVs were 0.95 and 1.02, and mean RAs were 1.00 and 1.00, for Eclipse and MIM results, respectively.
MIM outperformed Eclipse in both DSC and MDA, whereas the differences in liver volumes and calculated activities were statistically insignificant between the Eclipse and MIM results. Both auto-segmentation tools can be used to generate initial liver contours for resin Y-90 SIRT, which need to be reviewed and edited by physicians.
比较 Eclipse 治疗计划系统的 Smart Segmentation 和 MIM 软件的 Atlas Segment 进行钇-90（Y-90）树脂治疗的肝脏勾画。
对 20 例接受树脂 Y-90 选择性内放射治疗（SIRT）的患者的 CT 图像进行了测试。将 Smart Segmentation 和 Atlas Segment 生成的肝轮廓与医生手动勾画的轮廓进行比较。计算了 Dice 相似系数（DSC）、平均一致性距离（MDA）和体积比（RV）。对轮廓进行了活性计算，并计算了活性比（RA）。
Eclipse 和 MIM 的平均 DSC 分别为 0.77 和 0.83，MDA 分别为 0.88 和 0.71cm，平均 RV 分别为 0.95 和 1.02，平均 RA 分别为 1.00 和 1.00。
在 DSC 和 MDA 方面，MIM 优于 Eclipse，而 Eclipse 和 MIM 结果之间肝体积和计算活性的差异无统计学意义。这两种自动分割工具都可以用于生成钇-90 树脂 SIRT 的初始肝轮廓，这些轮廓需要由医生进行审查和编辑。
