Department of Cardiology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Department of Cardiology, Faculty of Medicine, Cyprus International University, Nicosia, Turkish Republic of Northern Cyprus.
Anatol J Cardiol. 2022 Jun;26(6):485-491. doi: 10.5152/AnatolJCardiol.2022.1631.
High-power short-duration radiofrequency ablation has improved lesion durability in pulmonary vein isolation. In this study, we investigate long-term clinical out-comes of high-power short-duration pulmonary vein isolation and posterior wall debulk- ing as an initial treatment modality in all corner atrial fibrillation patients.
This is a single-center, retrospective, observational study including all patients who have undergone high-power short-duration pulmonary vein and posterior wall deb-ulking, regardless of atrial fibrillation type and/or duration. High-power short-duration power delivery protocol was defined as 45 W at all ablation sites. Clinical and electrocar-diographic follow-up were performed in all patients.
One hundred forty-two patients were enrolled in this study. Paroxysmal atrial fibrillation was present in 88 (62%) of patients. The mean follow-up of this study was 36.9 months ± 12.2 months. During the follow-up period, 10 patients (11.4%) with a diag- nosis of paroxysmal atrial fibrillation had recurrence, while recurrence in patients with persistent and long-standing persistent atrial fibrillation was slightly higher (15 patients (28.1%) and 5 patients (50%), respectively). No major life-threatening complicationsoccurred.
This study has demonstrated excellent arrhythmia-free outcomes in unselected, real world atrial fibrillation patients undergoing high-power short-duration pulmonary vein and debulking posterior wall isolations, however larger randomized trials are warranted.
高功率短时间射频消融已提高了肺静脉隔离的病变耐久性。在这项研究中,我们研究了高功率短时间肺静脉隔离和后壁消融作为所有角型房颤患者初始治疗方式的长期临床结果。
这是一项单中心、回顾性、观察性研究,包括所有接受高功率短时间肺静脉和后壁消融的患者,无论房颤类型和/或持续时间如何。高功率短时间能量传递方案定义为所有消融部位的 45 W。所有患者均进行临床和心电图随访。
这项研究共纳入 142 例患者。阵发性房颤患者 88 例(62%)。本研究的平均随访时间为 36.9 个月±12.2 个月。随访期间,10 例(11.4%)阵发性房颤患者复发,而持续性和持久性房颤患者的复发率略高(分别为 15 例(28.1%)和 5 例(50%))。未发生重大危及生命的并发症。
这项研究表明,在未经选择的真实世界房颤患者中,高功率短时间肺静脉和后壁消融隔离术可获得出色的无心律失常结果,但需要更大规模的随机试验。