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埃塞俄比亚西北部 Dangila 区 1-9 岁儿童中活动性沙眼的流行情况及其相关因素分析:以示范和非示范 kebeles 为研究对象

Prevalence of active trachoma and its associated factors among 1-9 years of age children from model and non-model kebeles in Dangila district, northwest Ethiopia.

机构信息

Awi Zone, Dangila Woreda Health Office, Dangila, Ethiopia.

Department of Public Health, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

出版信息

PLoS One. 2022 Jun 15;17(6):e0268441. doi: 10.1371/journal.pone.0268441. eCollection 2022.

Abstract

BACKGROUND

Trachoma is the leading infectious disease that leads to blindness worldwide, especially in developing countries. Though Ethiopia had targeted a trachoma elimination program by 2020, the problem worsens, particularly in the Amhara Region. Even though sustained intervention measures are undertaken across the region, it is unclear why trachoma is still a significant public health problem. So, this study assessed the prevalence of active trachoma and associated factors among 1-9 years of age children from model and non-model kebeles in Dangila district Amhara Region, Northwest Ethiopia.

METHODS

A community-based comparative cross-sectional study was conducted from 20th September 2019 to 29th October 2019. A multistage stratified random sampling technique was used to reach 704 children from model and non-model kebeles. Samples were allocated proportionally to model and non-model kebeles. A structured and pretested data collection tool and observational checklist was used to manage the necessary data. Data were coded and entered in Epidata version 4.6, and further analysis was done using SPSS version 20 software. Bivariable and multivariable logistic regression analysis was employed to identify factors associated with active trachoma. Adjusted Odds Ratios (AOR), p-value, and respected Confidence Interval (CI) were used to report the findings.

RESULTS

Seven hundred four children were included in this study, with a response rate of 97.8%. The overall prevalence of active trachoma was 6% (95% CI: 4.5, 8.1). The prevalence of active trachoma among non-model and model Kebele was not significantly different. Still, the prevalence of active trachoma among children from model Kebele were [4.5%, (95% CI: 2.4%, 7.1%)] relatively lower compared with non-model kebeles, [7.6%, 95% CI: (4.9%, 10.9%)]. Moreover, not using latrine (AOR = 4.29, 95% CI: 1.96, 9.34), fly-eye contact (AOR = 2.59, 95% CI: 1.11, 6.03), presence of sleep in eyes (AOR = 2.46, 95% CI: 1.10, 5.47), presence of ocular discharge (AOR = 2.79, 95% CI: 1.30, 6.00), presence of nasal discharges (AOR = 2.67, 95% CI: 1.21, 5.90) and washing faces with soap (AOR = 0.22, 95% CI: 0.07, 0.69) were found significantly associated with the prevalence of active trachoma among children 1-9 years old.

CONCLUSIONS

The prevalence of active trachoma in the model and non-model kebeles was high and did not show a statistical difference. Attention to be given to latrine utilization, washing face with soap, and other personal hygiene activities.

摘要

背景

沙眼是全球导致失明的主要传染病,尤其在发展中国家更为严重。尽管埃塞俄比亚曾计划在 2020 年消除沙眼,但该问题仍在恶化,尤其是在阿姆哈拉地区。尽管该地区一直在采取持续的干预措施,但仍不清楚为什么沙眼仍然是一个严重的公共卫生问题。因此,本研究评估了在埃塞俄比亚西北部的 Dangila 区模型和非模型 kebeles 中 1-9 岁儿童中活动性沙眼的患病率及其相关因素。

方法

这是一项基于社区的比较性横断面研究,于 2019 年 9 月 20 日至 10 月 29 日进行。采用多阶段分层随机抽样技术,从模型和非模型 kebeles 中抽取了 704 名儿童。样本按模型和非模型 kebeles 进行比例分配。使用结构化和预测试的数据收集工具和观察清单来管理必要的数据。数据进行编码并输入到 Epidata 版本 4.6 中,然后使用 SPSS 版本 20 软件进行进一步分析。采用单变量和多变量逻辑回归分析来确定与活动性沙眼相关的因素。使用调整后的优势比(AOR)、p 值和相应的置信区间(CI)来报告结果。

结果

本研究共纳入 704 名儿童,应答率为 97.8%。活动性沙眼的总患病率为 6%(95%CI:4.5%,8.1%)。模型和非模型 kebeles 中活动性沙眼的患病率无显著差异。然而,模型 kebeles 中儿童的活动性沙眼患病率[4.5%(95%CI:2.4%,7.1%)]相对较低,而非模型 kebeles 的患病率[7.6%(95%CI:4.9%,10.9%)]。此外,不使用厕所(AOR=4.29,95%CI:1.96,9.34)、飞眼接触(AOR=2.59,95%CI:1.11,6.03)、眼睛有睡眠(AOR=2.46,95%CI:1.10,5.47)、眼睛有分泌物(AOR=2.79,95%CI:1.30,6.00)、有鼻腔分泌物(AOR=2.67,95%CI:1.21,5.90)和用肥皂洗脸(AOR=0.22,95%CI:0.07,0.69)与 1-9 岁儿童活动性沙眼的患病率显著相关。

结论

模型和非模型 kebeles 中活动性沙眼的患病率较高,且无统计学差异。应注意使用厕所、用肥皂洗脸和其他个人卫生活动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c89c/9200339/1878d426bd64/pone.0268441.g001.jpg

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