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桦树花粉季节期间过敏患者的嗜酸性粒细胞趋化活性:免疫疗法的影响。

Eosinophil chemotactic activity in allergic patients during the birch pollen season: the effect of immunotherapy.

作者信息

Rak S, Håkansson L, Venge P

出版信息

Int Arch Allergy Appl Immunol. 1987;82(3-4):349-50. doi: 10.1159/000234224.

DOI:10.1159/000234224
PMID:3570501
Abstract

Recently, heat-labile eosinophil chemotactic activity (ECA) has been found in serum after challenge of allergic asthmatic patients. In this study, we investigated changes in ECA in 40 birch-allergic patients during the birch pollen season; 20 of them had been treated with immunotherapy of birch pollen extract before the season. ECA raised significantly (p less than 0.001) in the untreated birch pollen-allergic patients during the season. Immunotherapy completely abolished this activity.

摘要

最近,在对过敏性哮喘患者进行激发试验后,发现其血清中存在热不稳定嗜酸性粒细胞趋化活性(ECA)。在本研究中,我们调查了40名桦树过敏患者在桦树花粉季节期间ECA的变化;其中20名患者在该季节之前接受了桦树花粉提取物免疫治疗。在该季节期间,未经治疗的桦树花粉过敏患者的ECA显著升高(p<0.001)。免疫治疗完全消除了这种活性。

相似文献

1
Eosinophil chemotactic activity in allergic patients during the birch pollen season: the effect of immunotherapy.桦树花粉季节期间过敏患者的嗜酸性粒细胞趋化活性:免疫疗法的影响。
Int Arch Allergy Appl Immunol. 1987;82(3-4):349-50. doi: 10.1159/000234224.
2
Immunotherapy abrogates the generation of eosinophil and neutrophil chemotactic activity during pollen season.免疫疗法可消除花粉季节期间嗜酸性粒细胞和中性粒细胞趋化活性的产生。
J Allergy Clin Immunol. 1990 Nov;86(5):706-13. doi: 10.1016/s0091-6749(05)80174-5.
3
The effect of immunotherapy on eosinophil accumulation and production of eosinophil chemotactic activity in the lung of subjects with asthma during natural pollen exposure.免疫疗法对自然花粉暴露期间哮喘患者肺部嗜酸性粒细胞积聚及嗜酸性粒细胞趋化活性产生的影响。
J Allergy Clin Immunol. 1991 Dec;88(6):878-88. doi: 10.1016/0091-6749(91)90244-i.
4
The formation of eosinophil and neutrophil chemotactic activity during a pollen season and after allergen challenge.花粉季节期间及变应原激发后嗜酸性粒细胞和中性粒细胞趋化活性的形成。
J Allergy Clin Immunol. 1989 May;83(5):933-9. doi: 10.1016/0091-6749(89)90108-5.
5
Priming of eosinophil adhesion in patients with birch pollen allergy during pollen season: effect of immunotherapy.
J Allergy Clin Immunol. 1997 Apr;99(4):551-62. doi: 10.1016/s0091-6749(97)70084-8.
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The effect of immunotherapy on bronchial hyperresponsiveness and eosinophil cationic protein in pollen-allergic patients.
J Allergy Clin Immunol. 1988 Sep;82(3 Pt 1):470-80. doi: 10.1016/0091-6749(88)90021-8.
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[The effect of specific immunotherapy on serum eotaxin level in patients with pollinosis: preliminary studies].[特异性免疫疗法对花粉症患者血清嗜酸性粒细胞趋化因子水平的影响:初步研究]
Pol Merkur Lekarski. 2001 Sep;11(63):244-6.
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Effects of immunotherapy on the inflammation in pollen asthma.免疫疗法对花粉性哮喘炎症的影响。
Allergy. 1993;48(17 Suppl):125-8; discussion 143-4. doi: 10.1111/j.1398-9995.1993.tb04714.x.
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The effect of anti-IgE treatment on in vitro leukotriene release in children with seasonal allergic rhinitis.抗IgE治疗对季节性变应性鼻炎患儿体外白三烯释放的影响。
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Comparison of nasal immunohistology in patients with seasonal rhinoconjunctivitis treated with topical steroids or specific allergen immunotherapy.局部用类固醇或特异性变应原免疫疗法治疗的季节性鼻结膜炎患者鼻腔免疫组织学比较
Allergy. 2005 May;60(5):643-9. doi: 10.1111/j.1398-9995.2005.00763.x.

引用本文的文献

1
Hay fever. A report of the Royal College of Physicians.花粉热。皇家内科医师学院报告。
J R Coll Physicians Lond. 1989 Apr;23(2):68-76.
2
Treatment of hay fever.花粉热的治疗。
J R Coll Gen Pract. 1989 Jul;39(324):292-6.
3
Desensitisation today.今日脱敏。
BMJ. 1990 Jun 2;300(6737):1412-3. doi: 10.1136/bmj.300.6737.1412.