Wood S F
J R Coll Gen Pract. 1989 Jul;39(324):292-6.
The range of treatments for hay fever available to the general practitioner has changed considerably in recent years. New antihistamines have addressed the problem of sedation and moved towards one daily dose; nasally applied corticosteroids avoid the need for systemic steroid therapy and its potential adverse effect; and regulatory decisions have set a trend away from immunotherapy in general practice. However, knowledge about the mechanism of action of immunotherapy is increasing and new developments with improved safety profiles include allergen polymers, allergoids, oral immunotherapy and nasal immunotherapy. Choice of treatment depends, as always, on the individual circumstances of the patient and his or her disease.
近年来,全科医生可用于治疗花粉热的疗法范围发生了很大变化。新型抗组胺药解决了镇静问题,并朝着每日一剂的方向发展;鼻用皮质类固醇避免了全身类固醇疗法及其潜在的不良反应;监管决策总体上使得全科医疗中免疫疗法的使用呈减少趋势。然而,关于免疫疗法作用机制的知识正在增加,安全性有所改善的新进展包括变应原聚合物、类变应原、口服免疫疗法和鼻内免疫疗法。治疗方法的选择一如既往地取决于患者的个人情况及其病情。