小儿唾液中天然获得的抗a型流感嗜血杆菌抗体。
Naturally acquired antibody against Haemophilus influenzae type a in pediatric saliva.
作者信息
Cabrera Adriana, Nix Eli B, Hickman Rebecca, Zlosnik James E A, Ulanova Marina, Sadarangani Manish
机构信息
Vaccine Evaluation Center, BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
Northern Ontario School of Medicine University, Thunder Bay, Ontario, Canada.
出版信息
J Immunol Methods. 2022 Aug;507:113306. doi: 10.1016/j.jim.2022.113306. Epub 2022 Jun 12.
We developed a salivary assay for the detection of naturally acquired IgA antibody against Haemophilus influenzae type a (Hia) capsular polysaccharide in healthy Indigenous children from Northwestern Ontario, Canada. Hia-specific IgA antibody was detected in the saliva of 93% of Indigenous children aged 2-7 years.
我们开发了一种唾液检测方法，用于检测加拿大安大略省西北部健康的原住民儿童中自然获得的抗a型流感嗜血杆菌（Hia）荚膜多糖的IgA抗体。在93%的2至7岁原住民儿童的唾液中检测到了Hia特异性IgA抗体。
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