Sussex Eye Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton, BN2 5BF, UK.
Brighton and Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PX, UK.
Sci Rep. 2022 Jun 15;12(1):10034. doi: 10.1038/s41598-022-13468-8.
This study aimed to assess the surface quality of cap, stroma and lenticular surfaces created using low-energy femtosecond laser lenticule extraction (Ziemer FEMTO LDV Z8). Twenty-four porcine eyes were divided into four groups (n = 6 each): two with optimal laser power (32%) with posterior curvature equivalent to a spherical correction of -2D and -5D, respectively and the other two with high power (64%) with spherical correction of -2D and -5D respectively. Samples were analysed using scanning electron microscopy (SEM). Surface morphology was evaluated using a standard scoring system; surface relief, surface regularity, extent and position of irregularities were graded by four independent clinicians. Eyes with 32% power and -2D correction had significantly less size of the irregular area than those with -5D; however, no significant difference was found between the two groups with 64% power. When comparing eyes with -2D correction, the size of the irregular area was lesser with 32% power. Surface relief was lesser with -5D correction with 32% power than 64% power. Low-energy femtosecond laser lenticule extraction (Ziemer FEMTO LDV Z8) produces good surface quality results. There is a tendency for smoother surface stromal quality with lower power settings than a higher power.
本研究旨在评估使用低能量飞秒激光微透镜提取术（Ziemer FEMTO LDV Z8）制作的帽、基质和晶状体表面的表面质量。将 24 只猪眼分为四组（每组 6 只）：两组采用最佳激光功率（32%），后表面曲率分别与球镜矫正 -2D 和 -5D 相当，另外两组采用高功率（64%），球镜矫正分别为 -2D 和 -5D。使用扫描电子显微镜（SEM）对样本进行分析。使用标准评分系统评估表面形态；四位独立临床医生对表面隆起、表面规则性、不规则性的程度和位置进行分级。功率为 32%且矫正 -2D 的眼的不规则区域面积明显小于矫正 -5D 的眼；然而，功率为 64%的两组之间没有发现显著差异。当比较矫正 -2D 的眼时，功率为 32%的眼的不规则区域面积较小。功率为 32%时，表面隆起程度低于功率为 64%且矫正 -5D 的眼。低能量飞秒激光微透镜提取术（Ziemer FEMTO LDV Z8）可产生良好的表面质量结果。与高功率相比，较低的功率设置可使基质表面质量更光滑。
