Parham Matthew J, Grush Andrew E, Smerica Abel, Wen Y Edward, Depani Monal, Ferry Andrew M, Jones Lloyd M, Thornton James F
Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.
Division of Plastic Surgery, Department of Surgery, Texas Children's Hospital, Houston, Texas.
Semin Plast Surg. 2022 Feb 15;36(1):3-7. doi: 10.1055/s-0042-1742736. eCollection 2022 Feb.
Wound healing is a highly complex process mediated by cellular interactions at the microscopic level. Increased understanding of wound healing physiology has served as the foundation for translational research to develop biologic wound care technologies that have profoundly affected patient care. As the reader will see throughout this series in , biologic wound technologies have broad applications and have greatly impacted the reconstructive ladder. Despite their frequent use, many surgeons lack familiarity with the myriad of products available on the market along with each product's relative advantages and shortcomings. This overview will discuss the classification of biologic wound agents used to reconstruct defects of the skin and soft tissue along with the advantages and disadvantages associated with their use.
伤口愈合是一个高度复杂的过程，由微观层面的细胞相互作用介导。对伤口愈合生理学的深入理解为转化研究奠定了基础，从而开发出对患者护理产生深远影响的生物伤口护理技术。正如读者将在本系列文章中看到的那样，生物伤口技术具有广泛的应用，并对重建阶梯产生了重大影响。尽管这些技术被频繁使用，但许多外科医生并不熟悉市场上众多可用产品及其各自的相对优缺点。本概述将讨论用于修复皮肤和软组织缺损的生物伤口制剂的分类，以及与其使用相关的优缺点。
