Singh Ranjan K
Internal Medicine, Antiretroviral Therapy Centre, District Hospital, Khagaria, IND.
Cureus. 2022 May 11;14(5):e24908. doi: 10.7759/cureus.24908. eCollection 2022 May.
In tropical areas, there are a variety of parasitic and nonparasitic causes of high-grade splenomegaly. An adolescent male patient with haemoglobin E/β-thalassaemia came with high-grade splenomegaly and severe anaemia, requiring blood transfusions on a regular basis. Treatment with folic acid and antioxidant vitamins reduced the requirement for blood transfusions, brought haemoglobin levels back to near normal, and reduced splenic enlargement. Haemoglobin E/β-thalassaemia is a haematological condition that causes anaemia and high-grade splenomegaly in the tropics. Initially, the disease was only seen in Southeast Asia, but it has since spread around the world due to migration from that region.
在热带地区，有多种寄生虫和非寄生虫病因可导致高度脾肿大。一名患有血红蛋白E/β地中海贫血的青少年男性患者出现了高度脾肿大和严重贫血，需要定期输血。使用叶酸和抗氧化维生素进行治疗减少了输血需求，使血红蛋白水平恢复到接近正常，并减轻了脾脏肿大。血红蛋白E/β地中海贫血是一种血液疾病，在热带地区会导致贫血和高度脾肿大。最初，这种疾病仅在东南亚出现，但由于该地区的人口迁移，此后已蔓延至全球。
