Yuan Juzheng, Wang Yang, Cao Yang, Yue Shuqiang, Li Xiao
Xi'an Medical University, Xi'an 710021, Shaanxi, China.
Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, Shaanxi, China.
Bioinorg Chem Appl. 2022 Jun 6;2022:7803001. doi: 10.1155/2022/7803001. eCollection 2022.
In order to study the application of nanoparticles in the diagnosis and treatment of pancreatic cancer, we retrospectively analyzed pancreatic cancer patients after operation.
60 cases of pancreatic cancer and surgical treatment were selected from our hospital. The time ranged from March 2018 to March 2019. The age ranged from 27 to 81 years. There were 36 males and 24 females, with an average age of 46.23 (7.63) years. Among them, the observation group consisted of nanotube artificial tubes, 16 males and 14 females, while the control group adopted nylon tube, male 18 and female 12. The patient was diagnosed by abdominal CT, and the patient's demographic data and basic clinical data were recorded at the same time.
In this study, 60 patients were divided into groups and compared. The patients underwent surgical resection of pancreaticoduodenum and reconstruction of pancreaticoduodenal papillary duct. Among them, the observation group used nanocomposite artificial tube, while the observation group used nanocomposite artificial tube and placed drainage tube to drain the peritoneal effusion to prevent the effusion from forming in abdominal hypertension and infection. The amount of postoperative bleeding, operation time, and postoperative concomitant symptoms were observed, and the differences between the two materials were analyzed.
The reconstruction of pancreaticoduodenal papillary duct with nanomaterials has certain advantages for postoperative recovery, reduces postoperative complications, reduces the probability of infection, and improves the therapeutic effect.
为研究纳米颗粒在胰腺癌诊断与治疗中的应用，我们对胰腺癌术后患者进行了回顾性分析。
选取我院60例接受胰腺癌手术治疗的患者。时间跨度为2018年3月至2019年3月。年龄范围为27至81岁。男性36例，女性24例，平均年龄46.23（7.63）岁。其中，观察组采用纳米管人工管，男性16例，女性14例，而对照组采用尼龙管，男性18例，女性12例。患者通过腹部CT进行诊断，同时记录患者的人口统计学数据和基本临床资料。
本研究将60例患者分组并进行比较。患者接受胰十二指肠手术切除及胰十二指肠乳头导管重建。其中，观察组使用纳米复合人工管，观察组使用纳米复合人工管并放置引流管引流腹腔积液，以防止腹腔高压和感染时积液形成。观察术后出血量、手术时间及术后伴随症状，并分析两种材料之间的差异。
采用纳米材料重建胰十二指肠乳头导管对术后恢复有一定优势，可减少术后并发症，降低感染概率，提高治疗效果。
