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眼部疾病中的性别差异、危险因素及管理,特别提及性甾体激素的作用

Gender Difference in Ocular Diseases, Risk Factors and Management with Specific Reference to Role of Sex Steroid Hormones.

作者信息

Korpole Nilay Reddy, Kurada Padma, Korpole Madhukar Reddy

机构信息

Department of Ophthalmology, Kasturba Medical College, MAHE, Manipal, Karnataka, India.

Drishti Eye Centre, Hyderabad, Telangana, India.

出版信息

J Midlife Health. 2022 Jan-Mar;13(1):20-25. doi: 10.4103/jmh.jmh_28_22. Epub 2022 May 2.

Abstract

Our eyes are windows to the world and to our soul. The approach to them offers an incredible space for conducting research to learn more about gender differences in ocular health and disease. There is inadequate data about gender differences to accurately plan and implement strategies to address the gender disparities. In this article, we discuss several conditions with ocular manifestations, focusing on those that disproportionately affect women more, with a specific emphasis on the role of sex hormones and the management of the conditions. Articles in the past two and a half decades were selected for this mini-review from the MEDLINE/PubMed database. The search terms used were: "Age Related Macular Degeneration," "Blindness," "Cataract," "Diabetic Retinopathy," "Dry Eye," "Glaucoma," "Ocular Diseases." To restrict the articles found, we limited search results with the terms: "Estrogen," "Gender difference," "Hormone," "Menopause," "Sex Steroid Hormones."

摘要

我们的眼睛是通往世界和我们灵魂的窗口。对眼睛的研究为深入了解眼部健康与疾病中的性别差异提供了广阔空间。然而,关于性别差异的数据不足,难以准确规划和实施应对性别差异的策略。在本文中,我们将讨论几种有眼部表现的病症,重点关注那些对女性影响更为显著的病症,特别强调性激素的作用以及这些病症的管理。为撰写本综述,我们从MEDLINE/PubMed数据库中选取了过去二十五年间的相关文章。使用的检索词为:“年龄相关性黄斑变性”“失明”“白内障”“糖尿病视网膜病变”“干眼症”“青光眼”“眼部疾病”。为限制检索到的文章数量,我们使用以下检索词进一步筛选结果:“雌激素”“性别差异”“激素”“更年期”“性类固醇激素”。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dce9/9190954/7f5c702bb3a9/JMH-13-20-g001.jpg

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