Ziv Y, Gillon G, Nissenkorn I, Servadio C
Isr J Med Sci. 1986 Dec;22(12):885-7.
Recently more conservative surgery of renal cell carcinoma is being performed. Patients with small, low-grade and low-stage tumors can be treated by enucleation or partial nephrectomy and will have about the same cure rate as those patients who were treated before by radical nephrectomy. Six patients, who would have been candidates for chronic dialysis, underwent enucleation or partial nephrectomy. Three of them had Stage I, and three had Stage II renal cell carcinomas. Patients were followed up 6 to 52 months (average 34) after surgery, and no local recurrence or distant metastases were found. It has recently been recognized that not every patient with renal cell carcinoma requires radical nephrectomy. Renal parenchyma can be saved without a decline in effective control of the tumor or a change in prognosis.
最近,肾细胞癌的手术治疗越来越趋于保守。对于肿瘤体积小、分级低且分期早的患者,可通过肿瘤剜除术或部分肾切除术进行治疗,其治愈率与之前接受根治性肾切除术的患者大致相同。6例原本适合进行慢性透析的患者接受了肿瘤剜除术或部分肾切除术。其中3例为Ⅰ期,3例为Ⅱ期肾细胞癌。术后对患者进行了6至52个月(平均34个月)的随访,未发现局部复发或远处转移。最近人们认识到,并非每个肾细胞癌患者都需要进行根治性肾切除术。在不降低肿瘤有效控制率或改变预后的情况下,可以保留肾实质。