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红细胞生成性原卟啉病患者腹腔镜手术期间免受光毒性损伤。

Protection from phototoxic injury during laparoscopic surgery in patients with erythropoietic protoporphyria.

作者信息

Pielaciński Konrad, Kwasny Mirosław, Górski Wojciech, Paluszkiewicz Piotr

机构信息

Department of General, Oncologic and Metabolic Surgery, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

Institute of Optoelectronics of the Jarosław Dąbrowski Military University of Technology, Warsaw, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2022 Jun;17(2):385-386. doi: 10.5114/wiitm.2022.115003. Epub 2022 Jun 1.

Abstract

Erythropoietic protoporphyria is a hereditary defect in heme synthesis, causing protoporphyrin deposition and phototoxic reactions after exposure to light, especially at a wavelength of about 400 nm. Sensitivity to light may cause postoperative complications. Therefore, in open surgery protective filters are employed on surgical luminaires. The dangers of laparoscopy are little understood and the intensity of the light used can be high. To protect against phototoxic injury, we inserted an OG 530 filter in the video track. This filter blocks wavelengths below 470 nm. Three cholecystectomies and one sigmoidectomies were performed laparoscopically. The procedures were uneventful, and the patients suffered no adverse reactions, including phototoxic symptoms. The filter had a moderate influence on color perception and caused no significant restrictions on working conditions. We consider that it is appropriate to develop a relevant design to meet the suitable requirements for a durable filter holder in the laparoscopic video track.

摘要

红细胞生成性原卟啉症是一种血红素合成的遗传性缺陷,导致原卟啉沉积,并在暴露于光线下后引发光毒性反应,尤其是在波长约为400纳米时。对光的敏感性可能会导致术后并发症。因此,在开放手术中,手术照明设备上会使用防护滤光片。腹腔镜检查的风险鲜为人知,且所使用的光强度可能很高。为防止光毒性损伤,我们在视频通道中插入了一个OG 530滤光片。该滤光片可阻挡低于470纳米的波长。我们进行了3例腹腔镜胆囊切除术和1例腹腔镜乙状结肠切除术。手术过程顺利,患者未出现任何不良反应,包括光毒性症状。该滤光片对颜色感知有一定影响,但对工作条件没有造成明显限制。我们认为,开发一种相关设计以满足腹腔镜视频通道中耐用滤光片支架的合适要求是恰当的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a62/9186081/23d3feeb641c/WIITM-17-46759-g001.jpg

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