Sigler E, Modai D, Zaidenstein R, Golik A, Marcus E L, Cohen N
Isr J Med Sci. 1986 Dec;22(12):906-8.
A 58-year-old woman presented with a history of premature onset of menopause, longstanding hepatosplenomegaly, monoclonal gammopathy, lower limb polyneuropathy of recent onset, diabetes mellitus, excessive perspiration and leg edema. Polyneuropathy and excessive perspiration improved following a course of prednisone and melphalan. The clinical and pathophysiological features fit the rare entity known as POEMS syndrome.
一名58岁女性，有过早绝经、长期肝脾肿大、单克隆丙种球蛋白病、近期新发的下肢多发性神经病、糖尿病、多汗和腿部水肿病史。在接受泼尼松和马法兰治疗后，多发性神经病和多汗症状有所改善。临床和病理生理特征符合一种名为POEMS综合征的罕见疾病。
