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强化医疗保健加维生素D给药有益于幼儿的生长发育并降低营养失调的发生率。

Intensive Health Care plus Vitamin D Administration Benefits the Growth and Development of Young Children and Reduces the Incidence of Nutritional Disorders.

作者信息

Liu Yangyang, Zeng Qingwen

机构信息

Children Rehabilitation Department of Shiyan Maternal and Child Health Care Hospital, Shiyan, Hubei Province, China.

Children Healthcare Center of Shiyan Maternal and Child Health Care Hospital, Shiyan, Hubei Province, China.

出版信息

Evid Based Complement Alternat Med. 2022 Jun 6;2022:8097035. doi: 10.1155/2022/8097035. eCollection 2022.

Abstract

This study was intended to assess the effect of intensive health care plus vitamin D administration on the growth, development, and nutritional status of young children. Totally, 131 young children who were admitted to Shiyan Maternal and Child Health Care Hospital from January 2020 to January 2021 were included and assigned via the random number table method at a ratio of 1 : 1 : 1 to receive either vitamin D administration (vitamin D group,  = 42), intensive health care (IHC) (IHC group,  = 44), or vitamin D administration plus intensive health care (combination group,  = 45). All children received a normal diet and routine care. After the intervention, all children showed robust improvement in their height, weight, neuropsychological development, and nutritional status, in which the combination therapy was associated with better outcomes in terms of physical development, neuropsychological development, and nutritional status, and a higher serum 25-hydroxyvitamin D3 (25-(OH)D3) level of the children versus monotherapy. Children receiving combined therapy had a significantly lower incidence of nutritional disorders than those receiving single therapy. Intensive health care plus vitamin D benefits the growth and development of young children and reduces the incidence of nutritional disorders in children.

摘要

本研究旨在评估强化保健加维生素D给药对幼儿生长发育及营养状况的影响。共纳入2020年1月至2021年1月在十堰市妇幼保健院住院的131名幼儿,并通过随机数字表法按1∶1∶1的比例将其分为三组,分别接受维生素D给药(维生素D组,n = 42)、强化保健(IHC)(IHC组,n = 44)或维生素D给药加强化保健(联合组,n = 45)。所有儿童均接受正常饮食和常规护理。干预后,所有儿童的身高、体重、神经心理发育及营养状况均有显著改善,其中联合治疗在身体发育、神经心理发育和营养状况方面的效果更好,且儿童血清25-羟维生素D3(25-(OH)D3)水平高于单一疗法。接受联合治疗的儿童营养障碍发生率明显低于接受单一治疗的儿童。强化保健加维生素D有益于幼儿的生长发育,并降低儿童营养障碍的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e729/9192294/d7c2cd9a0d82/ECAM2022-8097035.001.jpg

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