Stadler R, Bratzke B, Baumann I
Hautarzt. 1987 Feb;38(2):97-100.
Up till now no standard therapy for Behçet syndrome has existed. Long-term corticoid therapy is often necessary, although side-effects cannot be avoided. Recent investigations have shown a correlation between high endogenous gamma-interferon serum levels and low activity of the syndrome. A 20-year-old male with severe Behçet's syndrome was therefore treated with recombinant alpha-A-interferon (IFN). The general condition of the patient improved rapidly, together with rapid clearing of the skin lesions. Over a 10.5 week-period the patient received a total dose of 792 million IU recombinant alpha-A-interferon.
到目前为止，白塞综合征尚无标准治疗方法。长期使用皮质类固醇治疗往往是必要的，尽管副作用无法避免。最近的研究表明，内源性γ-干扰素血清水平高与该综合征的低活动度之间存在关联。因此，一名患有严重白塞综合征的20岁男性接受了重组α-A干扰素（IFN）治疗。患者的一般状况迅速改善，皮肤病变也迅速消退。在10.5周的时间里，患者共接受了7.92亿国际单位的重组α-A干扰素。
