College of Medicine, University of Kentucky, Lexington, Kentucky, USA.
Department of Surgery, University of Kentucky, Lexington, Kentucky, USA.
J Endourol. 2022 Oct;36(10):1322-1330. doi: 10.1089/end.2022.0134. Epub 2022 Jul 6.
Transurethral resection of prostate (TURP) remains the gold standard for the treatment of benign prostatic hyperplasia, but it is associated with complications. The association of health care resource utilization (HRU) and TURP has been poorly studied. We seek to evaluate HRU in patients undergoing TURP and identify factors contributing to outcomes. The National Surgical Quality Improvement Program (NSQIP) database was reviewed from 2012 to 2018 for TURP by Current Procedural Terminology code. All data will be deidentified with IRB exemption. HRU was defined as discharge to continued care, unplanned readmission within 30 days, or prolonged length of stay (LOS) (>75th percentile). We included preoperative variables, including age, body mass index, diabetes, and ASA class (a classification system to assess for fitness of patients perior to surgery). Operative duration (OD) was broken into deciles by minutes. Preoperative characteristics and outcomes were compared against OD. Predictors of HRU were found using a stepwise multivariate logistic regression. Overall, 38,749 patients were included. The following variables were significantly associated with OD (values are three shortest and three longest deciles, respectively): any HRU (35.9%, 32.4%, 31.4% and 32.4%, 33.7%, 37.6%) and prolonged LOS (31.3%, 27.6%, 26.5% and 28.0%, 30.4%, 34.1%). Findings in the first decile seemed to be an outlier, as shown in Figure 1. Complications associated with OD are shown in Figure 2. On multivariable analysis, patients with OD >58 minutes were more likely to have increased HRU; odds ratio 1.22, 1.33, 1.54, and 1.78 for deciles 58-66, 67-78, 78-99, and >100, respectively; p80, chronic obstructive pulmonary disease, dyspnea, hypertension, diabetes, not functionally independent, ASA class III and IV-V, and dirty/infected wound class, < 0.005. [Figure: see text] [Figure: see text] OD is an independent predictor of HRU in patients undergoing TURP and is more modifiable than other preoperative variables associated with increased HRU. Patients in the longest decile were more likely to have complications and increased HRU. Further study is needed to evaluate causation.
经尿道前列腺切除术(TURP)仍然是治疗良性前列腺增生的金标准,但它与并发症有关。医疗资源利用(HRU)与 TURP 的关联研究甚少。我们旨在评估接受 TURP 治疗的患者的 HRU,并确定导致结局的因素。从 2012 年到 2018 年,国家手术质量改进计划(NSQIP)数据库按当前程序术语(CPT)代码对 TURP 进行了审查。所有数据将通过 IRB 豁免进行去识别。HRU 定义为出院至持续护理、30 天内计划外再入院或延长住院时间(LOS)(>第 75 个百分位数)。我们纳入了术前变量,包括年龄、体重指数、糖尿病和 ASA 分级(一种评估患者手术前健康状况的分类系统)。手术时间(OD)按分钟分为十分位数。将术前特征和结果与 OD 进行比较。使用逐步多变量逻辑回归发现 HRU 的预测因素。 总体而言,纳入了 38749 名患者。以下变量与 OD 显著相关(值分别为三个最短和三个最长的十分位数):任何 HRU(35.9%、32.4%、31.4%和 32.4%、33.7%、37.6%)和延长 LOS(31.3%、27.6%、26.5%和 28.0%、30.4%、34.1%)。如图 1 所示,第 1 十分位数的结果似乎是一个异常值。与 OD 相关的并发症如图 2 所示。多变量分析显示,OD>58 分钟的患者更有可能增加 HRU;第 58-66、67-78、78-99 和>100 分位数的比值比分别为 1.22、1.33、1.54 和 1.78;p<0.005。[图:见正文][图:见正文] OD 是接受 TURP 治疗的患者 HRU 的独立预测因素,并且比其他与增加 HRU 相关的术前变量更具可操作性。最长十分位数的患者更有可能出现并发症和增加 HRU。需要进一步研究以评估因果关系。