Deeg M, Hagenmaier H, Kretschmer A
J Antibiot (Tokyo). 1987 Mar;40(3):320-8. doi: 10.7164/antibiotics.40.320.
Derivatives of the 16-membered dienlactone bafilomycins were prepared in order to study the structure-activity relationship of these compounds. Some derivatives formed by hydrolysis, O-alkylation, O-acylation, trans-esterification and epoxidation were isolated and their structures determined by two-dimensional (2D) NMR studies and mass spectroscopy.