LL-F28249抗生素复合物：一类新型抗寄生虫大环内酯类化合物。LL-F28249α、β、γ、λ的分离、表征及结构
LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda.
作者信息
Carter G T, Nietsche J A, Hertz M R, Williams D R, Siegel M M, Morton G O, James J C, Borders D B
机构信息
Medical Research Divisio, Lederle Laboratories, American Cyanamid Co., Pearl River, N.Y. 10965.
出版信息
J Antibiot (Tokyo). 1988 Apr;41(4):519-29. doi: 10.7164/antibiotics.41.519.
PMID:3372359
Abstract
A new family of antiparasitic macrolides has been isolated from Streptomyces cyaneogriseus sp. noncyanogenus. The compounds, designated LL-F28249 alpha, beta, gamma and lambda, possess potent antiparasitic activity. The isolation, purification and structure determination by spectroscopic methods are presented.
摘要
从浅蓝灰链霉菌非产氰变种中分离出了一个新的抗寄生虫大环内酯类化合物家族。这些化合物被命名为LL-F28249α、β、γ和λ，具有强大的抗寄生虫活性。本文介绍了其分离、纯化以及通过光谱方法进行的结构测定。
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