Tachibana M, Morioka H, Nishimura H, Kitamura T
Hear Res. 1987;26(2):171-6. doi: 10.1016/0378-5955(87)90109-2.
[3H]Inositol was perilymphatically perfused into the guinea pig cochlea and the sites of its incorporation were autoradiographically identified by electron microscope. In the organ of Corti, distinct areas of inositol incorporation were observed at sites enriched with cytoskeletal proteins. In addition, a wide range of cell organelles incorporated inositol. Cell membrane/subsurface cisterna complex of the outer hair cells and the cell membrane/microvilli complex incorporated inositol more avidly than did other cell membranes. In the stria vascularis, intermediate cells incorporated inositol more frequently than cells in other areas.
将[3H]肌醇经外淋巴灌注到豚鼠耳蜗中，并通过电子显微镜放射自显影鉴定其掺入部位。在柯蒂氏器中，在富含细胞骨架蛋白的部位观察到明显的肌醇掺入区域。此外，多种细胞器都掺入了肌醇。外毛细胞的细胞膜/亚表面池复合体以及细胞膜/微绒毛复合体比其他细胞膜更活跃地掺入肌醇。在血管纹中，中间细胞比其他区域的细胞更频繁地掺入肌醇。
