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使用XEN 63凝胶支架治疗难治性葡萄膜炎性青光眼:一例报告。

XEN 63 gel stent to treat a refractory uveitic glaucoma: A case report.

作者信息

Serrar Yasmine, Rezkallah Amina, Kodjikian Laurent, Poli Muriel, Mathis Thibaud, Denis Philippe

机构信息

Service d'Ophtalmologie, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, France.

UMR-CNRS 5510 Matéis, Université Claude Bernard Lyon 1, Villeurbanne, France.

出版信息

Eur J Ophthalmol. 2023 Jul;33(4):NP32-NP36. doi: 10.1177/11206721221109199. Epub 2022 Jun 16.

Abstract

PURPOSE

To describe the effectiveness of the XEN 63 gel stent in a refractory uveitic glaucoma after failure of an Ahmed Glaucoma Valve.

CASE DESCRIPTION

We report the case of a 54-year-old man with a history of uveitic glaucoma on his left eye due to Fuchs heterochromic iridocyclitis and neovascular glaucoma after a central retinal vein occlusion. Pre-operative intraocular pressure was 30 mmHg despite a QD (once-daily) dosed bimatoprost 0.3 mg and timolol 5 mg topical medication. At week 1, the eye exam showed an intraocular pressure of 6 mmHg with a well-formed bleb, a very mild hyphema and a localized choroidal detachment. At month 1, intraocular pressure was 14 mmHg with a formed bleb. Both hyphema and choroidal detachments had resolved. After a year, intraocular pressure was 16 mmHg without any medication and the bleb was still well-formed.

CONCLUSION

The XEN 63 gel stent provides a good intraocular pressure reduction and can be an efficient alternative for tube and filtration surgery in refractory glaucoma. Its long-term effectiveness needs to be evaluated.

摘要

目的

描述XEN 63凝胶支架在艾哈迈德青光眼阀植入失败后的难治性葡萄膜炎性青光眼治疗中的有效性。

病例描述

我们报告了一名54岁男性患者的病例,其左眼有葡萄膜炎性青光眼病史,病因是富克斯异色性虹膜睫状体炎以及视网膜中央静脉阻塞后继发新生血管性青光眼。尽管术前每天局部使用0.3毫克比马前列素和5毫克噻吗洛尔,但眼压仍为30 mmHg。术后第1周,眼部检查显示眼压为6 mmHg,滤过泡形成良好,有非常轻微的前房积血和局限性脉络膜脱离。术后第1个月,眼压为14 mmHg,滤过泡已形成。前房积血和脉络膜脱离均已消退。1年后,未使用任何药物时眼压为16 mmHg,滤过泡仍形成良好。

结论

XEN 63凝胶支架能有效降低眼压,可作为难治性青光眼引流管植入术和滤过手术的有效替代方案。其长期有效性有待评估。

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