Marchese Vincenzo, Randazzo Viviana, Badalamenti Rosanna, Anastasi Marco
Department of Ophthalmology, S Antonio Abate Hospital, Trapani, Sicily, Italy.
Department of Ophthalmology, Ospedali Riuniti Villa Sofia-Cervello, Palermo, Sicily, Italy.
J Curr Glaucoma Pract. 2024 Apr-Jun;18(2):74-78. doi: 10.5005/jp-journals-10078-1445. Epub 2024 Jul 10.
This case report describes the possibility of XEN63 lumen obstruction at the middle of the device and emphasizes the potential to restore its flow using an ab-externo revision technique involving a 10-0 nylon suture probe, before considering more aggressive surgical interventions.
A 55-year-old female with uveitic glaucoma underwent XEN63 implantation but experienced elevated intraocular pressure (IOP) (35 mm Hg) 1 month after the operation, despite medical therapy. A flat bleb, lack of response to medication, yttrium aluminum garnet (YAG) laser treatment, and slit-lamp needling necessitated revision.
An ab-externo surgical procedure was performed using a 10-0 nylon probe to release the obstruction, followed by the application of mitomycin C and removal of fibrous tissue and subconjunctival Tenon's capsule. Intraoperatively, flow was observed only after probing with the 10-0 nylon. Postoperatively, the patient's IOP decreased immediately and remained well-controlled at 2 months (8 mm Hg) without requiring further medication.
For patients experiencing increased inflammatory response, the XEN63 gel stent may develop deep lumen occlusion that is unresponsive to conventional treatments. This case report introduces a novel surgical technique applicable to various glaucoma devices, utilizing an ab-externo approach with a 10-0 nylon probe. The demonstrated success in reducing IOP suggests its potential as a less invasive alternative to consider before resorting to more aggressive surgical interventions.
Marchese V, Randazzo V, Badalamenti R, Reviving XEN63 Gel Stent Patency in Uveitic Glaucoma: A Novel Approach Using 10-0 Nylon Probe. J Curr Glaucoma Pract 2024;18(2):74-78.
本病例报告描述了XEN63装置中部管腔阻塞的可能性,并强调在考虑更激进的手术干预之前,使用涉及10-0尼龙缝线探针的外-外修复技术恢复其血流的潜力。
一名55岁患有葡萄膜炎性青光眼的女性接受了XEN63植入术,但术后1个月尽管进行了药物治疗,眼压仍升高(35 mmHg)。扁平滤过泡、对药物治疗无反应、钇铝石榴石(YAG)激光治疗及裂隙灯针刺均需要进行修复。
采用10-0尼龙探针进行外-外手术,以解除阻塞,随后应用丝裂霉素C并清除纤维组织和结膜下Tenon囊。术中,仅在用10-0尼龙探针探查后才观察到血流。术后,患者眼压立即下降,2个月时眼压控制良好(8 mmHg),无需进一步药物治疗。
对于炎症反应增强的患者,XEN63凝胶支架可能会出现深部管腔阻塞,对传统治疗无反应。本病例报告介绍了一种适用于各种青光眼装置的新型手术技术,采用10-0尼龙探针的外-外入路。在降低眼压方面取得的成功表明,在采取更激进的手术干预之前,它有可能作为一种侵入性较小的替代方法。
马尔切塞V、兰达佐V、巴达拉门蒂R,恢复葡萄膜炎性青光眼中XEN63凝胶支架的通畅性:使用10-0尼龙探针的新方法。《当代青光眼实践杂志》2024年;18(2):74-78。