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模拟青少年急性术后疼痛向慢性术后疼痛的转变:关于流行病学、围手术期及社会心理因素的叙述性综述

Modeling the transition from acute to chronic postsurgical pain in youth: A narrative review of epidemiologic, perioperative, and psychosocial factors.

作者信息

Rosenbloom Brittany N, Katz Joel

机构信息

Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.

Department of Psychology, York University, Toronto, Ontario, Canada.

出版信息

Can J Pain. 2022 Jun 9;6(2):166-174. doi: 10.1080/24740527.2022.2059754. eCollection 2022.

DOI:10.1080/24740527.2022.2059754
PMID:35711297
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9196786/
Abstract

A growing number of studies have identified high rates of pediatric chronic postsurgical pain (CPSP) after major surgery. Pediatric CPSP is associated with pain-related distress and comorbid mental health outcomes, such as anxiety and depression. From a biopsychosocial perspective, youth factors, such as genetics, epigenetics, sex, presurgical pain, sleep, anxiety, and pain catastrophizing, as well as parent factors, such as cognitive appraisals of their child's pain expression and pain catastrophizing, converge and lead to chronic pain disability. A comprehensive and testable psychosocial model of the transition from acute to chronic pediatric postsurgical pain has not been developed. This narrative review begins by evaluating the epidemiology and trajectories of pediatric CPSP and moves on to examine the more influential psychosocial models that have been proposed to understand the development of pediatric CPSP. Much of the literature to date has been conducted on adolescents undergoing spinal fusion. To conceptualize the transition from acute to chronic pain in youth, a combined diathesis-stress and interpersonal fear avoidance model is presented. Novel areas of future research include the potential influence that siblings and peers have on a youth's development of CPSP as well as the influence of gender.

摘要

越来越多的研究发现,大手术后小儿慢性术后疼痛(CPSP)的发生率很高。小儿CPSP与疼痛相关的痛苦以及共病的心理健康结果有关,如焦虑和抑郁。从生物心理社会的角度来看,青少年因素,如遗传学、表观遗传学、性别、术前疼痛、睡眠、焦虑和疼痛灾难化,以及父母因素,如对孩子疼痛表达的认知评估和疼痛灾难化,相互作用,导致慢性疼痛残疾。尚未建立一个从急性小儿术后疼痛到慢性疼痛转变的全面且可检验的社会心理模型。这篇叙述性综述首先评估小儿CPSP的流行病学和病程,接着考察为理解小儿CPSP的发展而提出的更具影响力的社会心理模型。迄今为止,大部分文献是针对接受脊柱融合术的青少年进行的。为了概念化青少年从急性疼痛到慢性疼痛的转变,提出了一个综合的素质-应激和人际恐惧回避模型。未来研究的新领域包括兄弟姐妹和同伴对青少年CPSP发展的潜在影响以及性别的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55af/9196786/f03d0ad175cd/UCJP_A_2059754_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55af/9196786/f03d0ad175cd/UCJP_A_2059754_F0001_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/55af/9196786/f03d0ad175cd/UCJP_A_2059754_F0001_B.jpg

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Acceptance and Commitment Therapy to manage pain and opioid use after major surgery: Preliminary outcomes from the Toronto General Hospital Transitional Pain Service.接受与承诺疗法用于管理大手术后的疼痛及阿片类药物使用:多伦多综合医院过渡性疼痛服务的初步结果
Can J Pain. 2017 Jun 28;1(1):37-49. doi: 10.1080/24740527.2017.1325317. eCollection 2017.
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Development of a Screening Tool for Pediatric Neuropathic Pain and Complex Regional Pain Syndrome: Pediatric PainSCAN.
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Reg Anesth Pain Med. 2025 Feb 5;50(2):132-143. doi: 10.1136/rapm-2024-105697.
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Prognostic factors of chronic postsurgical pain in children and adolescents: a systematic review and meta-analysis.儿童和青少年术后慢性疼痛的预后因素:一项系统评价和荟萃分析。
Reg Anesth Pain Med. 2025 Feb 5;50(2):144-152. doi: 10.1136/rapm-2024-105696.
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Relationships between orofacial pain and sleep: Analysis of UK biobank and genome-wide association studies data.口面部疼痛与睡眠之间的关系:对英国生物银行和全基因组关联研究数据的分析。
J Dent Sci. 2025 Jan;20(1):529-538. doi: 10.1016/j.jds.2024.04.027. Epub 2024 May 6.
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When thinking about pain contributes to suffering: the example of pain catastrophizing.当思考疼痛会增加痛苦时:以疼痛灾难化为例。
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