University of Health Sciences, Istanbul Fatih Sultan Mehmet Training and Research Hospital, Department of Radiology, Istanbul, Turkey.
Breast J. 2022 Feb 4;2022:1888726. doi: 10.1155/2022/1888726. eCollection 2022.
The purpose of this study was to investigate the feasibility of the percutaneous radiofrequency (RF) excision system (BLES) as a primary method of diagnosis and removal of small breast masses.
Ninety-six lesions in 95 patients with 50.5 ± 8.4 years of age were treated in a five-year period by a single operator. Inclusion criteria were as follows: size (<20 mm), depth (>10 mm), and indeterminate or suspicious radiological features (74 BI-RADS 3 and 22 BI-RADS 4). The procedure was performed under ultrasound (US) guidance using 6 G retriever probes with 12-, 15-, and 20-mm baskets.
Lesions were between 5 and 20 (12.3 ± 3.8) mm in length. They were removed at the first attempt in all but one case. The technical success rate was 98.95%, and the diagnostic success rate was 100%. Ninety-one lesions were histologically benign and five were neoplastic. Two lesions that were previously classified as BI-RADS 3 were diagnosed as neoplasia (atypical lobular hyperplasia), and nineteen lesions that were previously classified as BI-RADS 4a were diagnosed as benign. The complete excision rate (presence of tumor-free negative surgical margin) was 40% in neoplastic lesions. There were no major complications. The minor complication rate was 1.58%. No recurrence was observed during 18 months of follow-up.
BLES delivers surgical quality specimens for confident histopathological examination and is a safe alternative to surgical resection in lesions with suitable size.
本研究旨在探讨经皮射频（RF）切除术系统（BLES）作为诊断和切除小乳腺肿块的主要方法的可行性。
在五年期间，由一名外科医生对 95 名患者的 96 个病灶进行了治疗，这些患者的年龄为 50.5±8.4 岁。纳入标准为：大小（<20mm）、深度（>10mm）以及不确定或可疑的影像学特征（74 个 BI-RADS 3 和 22 个 BI-RADS 4）。该过程在超声（US）引导下进行，使用 6G 取物探针和 12、15 和 20mm 的篮子。
病灶长度为 5-20（12.3±3.8）mm。除了一个病例外，所有病例均在首次尝试时被切除。技术成功率为 98.95%，诊断成功率为 100%。91 个病灶为组织学良性，5 个为肿瘤性。两个先前被归类为 BI-RADS 3 的病灶被诊断为肿瘤（不典型小叶增生），19 个先前被归类为 BI-RADS 4a 的病灶被诊断为良性。肿瘤性病变的完全切除率（无肿瘤阴性切缘）为 40%。无重大并发症。小并发症发生率为 1.58%。在 18 个月的随访期间未观察到复发。
BLES 提供了用于进行有信心的组织病理学检查的外科质量标本，并且是适合大小的病变的安全替代手术切除方法。
