Zhang Fuman, Li Chengyi, Wu Xinquan, Miao Kali, Zhang Zhe, Zhang Jing
Department of Breast Surgery, Mindong Hospital Affiliated to Fujian Medical University, No. 89, Heshan Road, Fu'an, 355000, Fujian Province, China.
Department of Breast Diseases, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, 361000, Fujian, China.
Sci Rep. 2025 Jan 3;15(1):728. doi: 10.1038/s41598-024-79778-1.
Granulomatous mastitis (GM) poses challenges in diagnosis and treatment due to its similarities with other breast diseases like cancer. The comparative study evaluated the efficacy and safety of a vacuum-assisted biopsy device with minimally invasive excisions compared to traditional wide local excisions. The vacuum-assisted biopsy device technique offers benefits such as precise tissue removal, reduced damage to healthy tissue, shorter surgery and recovery times, and lower postoperative complication risks. The study found that the vacuum-assisted biopsy device had comparable efficacy to traditional wide local excision in treating GM with an overall effectiveness rate of 92.9% and a recurrence rate of 9.52%. The vacuum-assisted biopsy device group showed advantages in reduced hospitalization duration (2.83 days vs. 7.52 days), lower costs, and better cosmetic outcomes, with a 100% patient satisfaction rate compared to 80% in the control group. This study fills existing clinical evidence gaps regarding the effectiveness and safety of vacuum-assisted biopsy device in GM treatment. By providing evidence-based guidelines, it aims to assist clinicians in choosing the most appropriate treatment for GM patients, ultimately improving their quality of life and mental well-being. The research contributes valuable insights into GM therapy, potentially revolutionizing treatment approaches and enhancing patient outcomes.
肉芽肿性乳腺炎（GM）因其与癌症等其他乳腺疾病相似，在诊断和治疗方面面临挑战。这项对比研究评估了与传统广泛局部切除相比，真空辅助活检装置进行微创切除的疗效和安全性。真空辅助活检装置技术具有精确切除组织、减少对健康组织的损伤、缩短手术和恢复时间以及降低术后并发症风险等优点。研究发现，真空辅助活检装置在治疗GM方面与传统广泛局部切除具有相当的疗效，总有效率为92.9%，复发率为9.52%。真空辅助活检装置组在缩短住院时间（2.83天对7.52天）、降低成本和改善美容效果方面具有优势，患者满意度为100%，而对照组为80%。这项研究填补了关于真空辅助活检装置在GM治疗中的有效性和安全性的现有临床证据空白。通过提供循证指南，旨在帮助临床医生为GM患者选择最合适的治疗方法，最终改善他们的生活质量和心理健康。该研究为GM治疗提供了有价值的见解，可能会彻底改变治疗方法并提高患者预后。
