• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Editorial: Insights in Inflammation Pharmacology: 2021.社论：炎症药理学洞察：2021年。
Front Pharmacol. 2022 May 27;13:928535. doi: 10.3389/fphar.2022.928535. eCollection 2022.
2
Comparative protection against liver inflammation and fibrosis by a selective cyclooxygenase-2 inhibitor and a nonredox-type 5-lipoxygenase inhibitor.选择性环氧化酶-2抑制剂与非氧化还原型5-脂氧合酶抑制剂对肝脏炎症和纤维化的比较性保护作用
J Pharmacol Exp Ther. 2007 Dec;323(3):778-86. doi: 10.1124/jpet.107.128264. Epub 2007 Aug 31.
3
[The effects of cyclooxygenase and lipoxygenase inhibitors: the prerequisites for more effective anti-inflammatory combinations].
Eksp Med Morfol. 1990;29(1):44-53.
4
Cyclooxygenase and lipoxygenase pathways in anterior uvea and conjunctiva.眼前葡萄膜和结膜中的环氧化酶和脂氧合酶途径。
Prog Clin Biol Res. 1989;312:39-52.
5
Expression of cyclooxygenase and lipoxygenase enzymes in sinonasal mucosa of patients with cystic fibrosis.囊性纤维化患者鼻窦黏膜中环氧化酶和脂氧合酶的表达。
Arch Otolaryngol Head Neck Surg. 2008 Aug;134(8):825-31. doi: 10.1001/archotol.134.8.825.
6
Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS.采用亲和超滤与 HPLC/MS 联用的方法从知母根茎中鉴定甾体皂苷糖苷元和呋甾烷醇糖苷元，作为 5-脂氧合酶和环氧化酶-2 的双重靶向抑制剂。
Phytomedicine. 2020 Oct;77:153284. doi: 10.1016/j.phymed.2020.153284. Epub 2020 Jul 11.
7
Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A group IIA, 5-lipoxygenase and cyclooxygenase-2.雷公藤红素通过抑制花生四烯酸途径介质的催化活性来调节炎症：分泌型磷脂酶A IIA组、5-脂氧合酶和环氧化酶-2。
Pharmacol Res. 2016 Nov;113(Pt A):265-275. doi: 10.1016/j.phrs.2016.08.035. Epub 2016 Sep 3.
8
Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production.环氧化酶-2 抑制可破坏实验性自身免疫性关节炎小鼠的炎症消退，并通过前列腺素 E2 介导的脂氧素 A4 产生来恢复。
J Immunol. 2010 Jun 1;184(11):6418-26. doi: 10.4049/jimmunol.0903816. Epub 2010 Apr 30.
9
Pharmacology of PF-4191834, a novel, selective non-redox 5-lipoxygenase inhibitor effective in inflammation and pain.PF-4191834 的药理学研究：一种新型、选择性非氧化 5-脂氧合酶抑制剂，在炎症和疼痛中具有疗效。
J Pharmacol Exp Ther. 2010 Jul;334(1):294-301. doi: 10.1124/jpet.110.166967. Epub 2010 Apr 8.
10
Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.在犬类炎症模型中对双环氧化酶-2选择性/5-脂氧合酶抑制剂RWJ 63556的抗炎活性进行评估。
J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101.

引用本文的文献

1
Molecular Modeling of Brassicaceae Derivatives for Inhibiting Lipoxygenases: A Promising Therapeutic Strategy.芸薹属衍生物抑制脂氧合酶的分子建模：一种有前途的治疗策略。
Curr Drug Discov Technol. 2024;21(4):48-e011223224117. doi: 10.2174/0115701638269042231122064738.

本文引用的文献

1
Inflammation and Cancer: From the Development of Personalized Indicators to Novel Therapeutic Strategies.炎症与癌症：从个性化指标的发展到新型治疗策略
Front Pharmacol. 2022 Mar 3;13:838079. doi: 10.3389/fphar.2022.838079. eCollection 2022.
2
Dendritic cell migration in inflammation and immunity.树突状细胞在炎症和免疫中的迁移。
Cell Mol Immunol. 2021 Nov;18(11):2461-2471. doi: 10.1038/s41423-021-00726-4. Epub 2021 Jul 23.
3
Therapeutic approach of anaphylaxis.过敏反应的治疗方法。
Curr Opin Allergy Clin Immunol. 2019 Aug;19(4):393-401. doi: 10.1097/ACI.0000000000000539.
4
Curbing tumorigenesis and malignant progression through the pharmacological control of the wound healing process.通过对伤口愈合过程的药理学控制来抑制肿瘤发生和恶性进展。
Vascul Pharmacol. 2017 Feb;89:1-11. doi: 10.1016/j.vph.2017.01.003. Epub 2017 Jan 12.
5
TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P.TGF-β 驱动的肺纤维化依赖于巨噬细胞，并被血清淀粉样蛋白 P 阻断。
Int J Biochem Cell Biol. 2011 Jan;43(1):154-62. doi: 10.1016/j.biocel.2010.10.013. Epub 2010 Oct 29.
6
Immunomodulatory mast cells: negative, as well as positive, regulators of immunity.免疫调节性肥大细胞：免疫的负调节因子和正调节因子
Nat Rev Immunol. 2008 Jun;8(6):478-86. doi: 10.1038/nri2327.

Editorial: Insights in Inflammation Pharmacology: 2021.

作者信息

Patrignani Paola, Steinhilber Dieter

机构信息

Department of Neuroscience, Imaging and Clinical Science, and CAST, "G. d'Annunzio" University, Chieti, Italy.

Institut fuer Pharmazeutische Chemie, Universitaet Frankfurt, Frankfurt am Main, Germany.

出版信息

Front Pharmacol. 2022 May 27;13:928535. doi: 10.3389/fphar.2022.928535. eCollection 2022.

DOI:10.3389/fphar.2022.928535
PMID:35712698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9197213/
Abstract
摘要