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14 年纵向研究青少年 1 型糖尿病患者与非患者抑郁症状的变化。

14-Year Longitudinal Trajectories of Depressive Symptoms Among Youth With and Without Type 1 Diabetes.

机构信息

Carnegie Mellon University, USA.

University of Pittsburgh, USA.

出版信息

J Pediatr Psychol. 2022 Oct 19;47(10):1135-1144. doi: 10.1093/jpepsy/jsac054.

DOI:10.1093/jpepsy/jsac054
PMID:35713643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9960008/
Abstract

OBJECTIVE

There is evidence that youth with type 1 diabetes are at risk for depression, and depression is a significant risk factor for subsequent psychological and physical health problems. However, it is not clear if/when this depression risk emerges. The goal of this study was to determine if there are differences in levels of depressive symptoms between youth with and without type 1 diabetes that develop over the course of emerging adulthood. We also examined whether adolescent psychosocial variables predicted depressive symptoms during emerging adulthood.

METHODS

Youth with (n = 132) and without (n = 131) type 1 diabetes were enrolled in the study at average age 12 and followed for 14 years. Depressive symptoms were measured throughout the study. Psychosocial variables of interest were measured during adolescence.

RESULTS

Group differences in depressive symptoms emerged by study end at average age 26. Depressive symptoms appeared to decline over time for youth without diabetes and to increase over time for youth with diabetes. Parent relationship difficulties increased over adolescence as did peer conflict for the entire cohort. Supportive relationships with parent and peers predicted fewer end of study depressive symptoms (controlling for baseline depressive symptoms)-equally so for both groups.

CONCLUSIONS

This study provides evidence that those with type 1 diabetes may be at risk for depressive symptoms many years after diagnosis and after adolescence. Although relational difficulties with parents and peers increase during adolescence, supportive relationships over the course of adolescence may help to mitigate depressive symptoms during young adulthood.

摘要

目的

有证据表明,1 型糖尿病青少年存在抑郁风险,而抑郁是随后出现心理和身体健康问题的重要危险因素。然而,目前尚不清楚这种抑郁风险是否/何时出现。本研究的目的是确定在成年早期期间,是否有 1 型糖尿病患者和非 1 型糖尿病患者的抑郁症状水平存在差异。我们还检查了青少年心理社会变量是否在成年早期预测抑郁症状。

方法

在平均年龄为 12 岁时,招募了患有(n=132)和未患有(n=131)1 型糖尿病的青少年参加该研究,并随访了 14 年。在整个研究过程中测量了抑郁症状。在青少年时期测量了感兴趣的心理社会变量。

结果

在平均年龄为 26 岁的研究结束时,出现了抑郁症状的组间差异。对于没有糖尿病的青少年,抑郁症状似乎随时间而下降,而对于患有糖尿病的青少年,抑郁症状则随时间而增加。整个队列的父母关系困难和同伴冲突在青春期期间都有所增加。与父母和同伴的支持性关系预测了较少的研究结束时的抑郁症状(控制了基线抑郁症状)-对于两个组来说都是如此。

结论

本研究提供了证据表明,在诊断后和青春期后多年,1 型糖尿病患者可能存在抑郁症状的风险。尽管父母和同伴之间的关系困难在青春期期间增加,但在青春期期间的支持性关系可能有助于减轻成年早期的抑郁症状。