Biodesign Center for Environmental Health Engineering, Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.
College of Health Solutions, Arizona State University, Phoenix, AZ 85004, USA.
Infect Genet Evol. 2022 Sep;103:105315. doi: 10.1016/j.meegid.2022.105315. Epub 2022 Jun 14.
Virus surveillance by wastewater-based epidemiology (WBE) in two Arizona municipalities in Maricopa County, USA (~700,000 people), revealed the presence of six canine picornavirus (CanPV) variants: five in 2019 and one in 2021. Phylogenetic analysis suggests these viruses might be from domestic dog breeds living within or around the area. Phylogenetic and pairwise identity analyses suggest over 15 years of likely enzootic circulation of multiple lineages of CanPV in the USA and possibly globally. Considering <10 CanPV sequences are publicly available in GenBank as of June 2, 2022, the results provided here constitute an increase of current knowledge on CanPV diversity and highlight the need for increased surveillance.
通过在美国亚利桑那州马里科帕县的两个城市（约 70 万人）的污水流行病学（WBE）监测病毒，发现了六种犬小 RNA 病毒（CanPV）变体：五种在 2019 年，一种在 2021 年。系统进化分析表明，这些病毒可能来自该地区内或周围的家养犬种。系统进化和成对同一性分析表明，在美国和可能在全球范围内，多种 CanPV 谱系可能已经存在 15 年以上的地方流行。考虑到截至 2022 年 6 月 2 日，GenBank 中公开提供的 CanPV 序列<10 个，这里提供的结果增加了当前对 CanPV 多样性的认识，并强调了加强监测的必要性。
