Yasui Y, Itoh K, Sugimoto T, Kaneko T, Mizuno N
J Comp Neurol. 1987 Mar 8;257(2):253-68. doi: 10.1002/cne.902570210.
Projections from the parvicellular division of the posteromedial ventral thalamic nucleus (VPMpc) of the cat were examined. After injection of horseradish peroxidase conjugated with wheat germ agglutinin (WGA-HRP) into the VPMpc, both anterogradely labeled axon terminals and retrogradely labeled neuronal cell bodies were found ipsilaterally in three discrete regions of the cerebral cortex, i.e., in the orbital cortex, caudoventral part of the infralimbic cortex, and medial part of the fundus of the posterior rhinal sulcus (perirhinal area); in the subcortical regions, anterogradely labeled axon terminals were seen ipsilaterally in the rostrodorsal part of the lateral amygdaloid nucleus. Neuronal connections between these VPMpc-recipient regions were further verified by injecting WGA-HRP into each of the three cortical and the lateral amygdaloid regions. After injection of WGA-HRP into each of the three cortical regions, labeled neuronal cell bodies and axon terminals were seen ipsilaterally in the VPMpc, especially in its medial part, and in the other two of the three VPMpc-recipient cortical regions. In the rostrodorsal part of the lateral amygdaloid nucleus, both axon terminals and neuronal cell bodies were labeled after WGA-HRP injection into the perirhinal area, and only axon terminals were labeled after WGA-HRP injection into the orbital cortex, but no labeling was observed after WGA-HRP injection into the infralimbic cortex. After injection of WGA-HRP into the rostrodorsal portion of the lateral amygdaloid nucleus, both axon terminals and neuronal cell bodies were labeled ipsilaterally in the perirhinal area and the ectorhinal area, and only neuronal cell bodies were labeled ipsilaterally in the VPMpc (especially in its medial part) and orbital cortical region; no labeling was observed in the infralimbic cortex. The present results indicate that the VPMpc of the cat is connected reciprocally with the orbital, infralimbic, and perirhinal cortical regions on the ipsilateral side, that the three VPMpc-recipient cortical regions are reciprocally connected with each other, that the VPMpc sends fibers ipsilaterally to the rostrodorsal part of the lateral amygdaloid nucleus, which may relay information from the VPMpc to the perirhinal cortical area, and that the VPMpc-recipient area in the lateral amygdaloid nucleus receives cortical fibers from the orbital and perirhinal cortical regions.
对猫后内侧腹侧丘脑核（VPMpc）的小细胞部投射进行了研究。将与小麦胚凝集素结合的辣根过氧化物酶（WGA-HRP）注入VPMpc后，在大脑皮质的三个离散区域同侧发现了顺行标记的轴突终末和逆行标记的神经元胞体，即眶皮质、内嗅皮质的尾腹侧部以及后梨状沟底部内侧部（梨周区）；在皮质下区域，同侧外侧杏仁核的吻背侧部可见顺行标记的轴突终末。通过将WGA-HRP注入三个皮质区域和外侧杏仁核区域中的每一个，进一步证实了这些VPMpc接受区之间的神经元连接。将WGA-HRP注入三个皮质区域中的每一个后，在VPMpc同侧，特别是其内侧部，以及三个VPMpc接受皮质区域中的另外两个区域，可见标记的神经元胞体和轴突终末。在外侧杏仁核的吻背侧部，将WGA-HRP注入梨周区后，轴突终末和神经元胞体均被标记，将WGA-HRP注入眶皮质后，仅轴突终末被标记，但将WGA-HRP注入内嗅皮质后未观察到标记。将WGA-HRP注入外侧杏仁核的吻背侧部后，梨周区和嗅外区同侧的轴突终末和神经元胞体均被标记，VPMpc（特别是其内侧部）和眶皮质区域同侧仅神经元胞体被标记；在内嗅皮质未观察到标记。目前的结果表明，猫的VPMpc与同侧的眶、内嗅和梨周皮质区域相互连接，三个VPMpc接受皮质区域相互连接，VPMpc同侧发出纤维至外侧杏仁核的吻背侧部，后者可能将信息从VPMpc传递至梨周皮质区，并且外侧杏仁核中的VPMpc接受区接受来自眶皮质和梨周皮质区域的皮质纤维。
