Shi C J, Cassell M D
Department of Anatomy, University of Iowa, Iowa City 42242, USA.
J Comp Neurol. 1997 Jun 2;382(2):153-75.
The cortical, thalamic, and amygdaloid connections of the rodent temporal cortices were investigated by using the anterograde transport of iontophoretically injected biocytin. Injections into area Te1 labeled axons and terminals in the ventral regions of the dorsal and ventral subnuclei of the medial geniculate complex, area Te3, the rostrodorsal part of area Te2, and the ventrocaudal caudate putamen. No amygdaloid labeling was observed. Thalamic projections from Te2 targeted the lateral posterior nucleus, the dorsal part of the dorsal subnucleus of the medial geniculate complex, and the peripeduncular nucleus. Corticocortical projections mainly terminated in the dorsal perirhinal cortex, but moderately dense projections were observed in medial and lateral peristriate cortex, and only light projections were observed to Te1 and Te3. Projections to these isocortical regions terminated in layers I and VI. Amygdaloid projections targeted the ventromedial subdivision of the lateral nucleus and the adjacent part of the anterior basolateral nucleus. Area Te3 was observed to project to the ventrolateral parts of the dorsal and ventral subnuclei of the medial geniculate complex, the dorsal perirhinal cortex, rostral Te2, and Te1. In the amygdala, labeled fibers and terminals were concentrated in the dorsolateral subdivision of the lateral nucleus. These data confirm that areas Te1 and Te3 are hierarchically organized cortical areas connected with auditory relay nuclei in the thalamus. Area Te2, in contrast, appears to be weakly connected with Te1 and Te3 but is heavily connected with the peristriate cortex and tectorecipient thalamic nuclei. Te2 appears to be a visually related cortical area. The data also indicate that projections from Te2 and Te3 target different subregions of the lateral nucleus and that Te2, but not Te3, projects to the basolateral nucleus.
通过离子电渗法注入生物胞素的顺行运输，研究了啮齿动物颞叶皮质的皮质、丘脑和杏仁核连接。向颞极区1（Te1）注射标记了内侧膝状体复合体背侧和腹侧亚核腹侧区域、颞极区3（Te3）、颞极区2（Te2）的吻背侧部分以及腹尾侧尾壳核中的轴突和终末。未观察到杏仁核标记。来自Te2的丘脑投射靶向外侧后核、内侧膝状体复合体背侧亚核的背侧部分以及脚周核。皮质-皮质投射主要终止于背侧嗅周皮质，但在内侧和外侧纹周皮质观察到中等密度的投射，而向Te1和Te3仅观察到少量投射。向这些同型皮质区域的投射终止于I层和VI层。杏仁核投射靶向外侧核的腹内侧亚区和前基底外侧核的相邻部分。观察到Te3投射到内侧膝状体复合体背侧和腹侧亚核的腹外侧部分、背侧嗅周皮质、吻侧Te2和Te1。在杏仁核中，标记的纤维和终末集中在外侧核的背外侧亚区。这些数据证实，Te1和Te3是与丘脑中听觉中继核相连的分层组织皮质区域。相比之下，Te2似乎与Te1和Te3的连接较弱，但与纹周皮质和接受顶盖投射的丘脑核有大量连接。Te2似乎是一个与视觉相关的皮质区域。数据还表明，来自Te2和Te3的投射靶向外侧核的不同亚区，并且Te2而非Te3投射到基底外侧核。
