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二次减肥手术——初次手术的类型会影响转流术后的结果吗?

Secondary Bariatric Surgery-Does the Type of Index Procedure Affect Outcomes After Conversion?

作者信息

Oyefule Omobolanle, Do Timothy, Karthikayen Raveena, Portela Ray, Dayyeh Barham Abu, McKenzie Travis, Kellogg Todd, Ghanem Omar M

机构信息

Department of Surgery, Emory University School of Medicine, 550 Peachtree Street NE, Atlanta, GA, 30308, USA.

Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

出版信息

J Gastrointest Surg. 2022 Sep;26(9):1830-1837. doi: 10.1007/s11605-022-05385-y. Epub 2022 Jun 17.

Abstract

BACKGROUND

Although revisions account for 17% of cases performed at bariatric centers of excellence, scarce data exists on whether index operation type influences outcomes after secondary operations.

OBJECTIVE

We designed a study investigating the effect of primary procedure type on weight loss and perioperative complications after conversion bariatric surgery.

SETTING

Tertiary Referral Hospital, USA.

METHODS

We performed a retrospective review of patients undergoing conversion from sleeve gastrectomy (SG) or adjustable gastric band (AGB) to Roux-en-Y gastric bypass (RYGB) from 2009 to 2019. Post-operatively, we measured short- and medium-term complications and changes in body weight at various time points. Univariate and regression analyses were performed.

RESULTS

Forty-two (SG) patients and 116 (AGB) patients underwent conversion to RYGB, most commonly for GERD (57.1%) in SG patients vs. weight regain (77.6%) in AGB patients. Mean pre-conversion BMI was 36.7 kg/m (SG) vs 43.8 kg/m (AGB). Mean time to conversion (months) was 52.9 (SG) vs 94.7 (AGB). Complication rate was 9.5% (SG) vs 6% (AGB) at 30 days (p = 0.48) and 31%(SG) vs 14.5% (AGB) (p = 0.02) at 2 years. Mean post conversion %TWL was 11.6% (SG) vs 24.6% (AGB) in patients with GERD/dysphagia (p = 0.014) and 20.7% (SG) vs 27.6% (AGB) in patients converted for weight-related reasons (p = 0.027) at 1 year. Overall mean %TWL was 13.2% (SG) vs 24.7% (AGB) at 2 years (p < 0.0035).

CONCLUSION

After conversion to RYGB, patients with AGB experience better short- and medium-term weight loss than those with SG, even after accounting for conversion indications. SG to RYGB conversions have a higher resolution of reflux disease.

摘要

背景

尽管翻修手术占卓越减肥中心所施行手术病例的17%,但关于初次手术类型是否会影响二次手术后的结果,现有数据稀少。

目的

我们设计了一项研究,调查初次手术类型对减肥手术转换术后体重减轻及围手术期并发症的影响。

地点

美国三级转诊医院。

方法

我们对2009年至2019年间接受从袖状胃切除术(SG)或可调节胃束带术(AGB)转换为Roux-en-Y胃旁路术(RYGB)的患者进行了回顾性研究。术后,我们在不同时间点测量了短期和中期并发症以及体重变化。进行了单因素分析和回归分析。

结果

42例(SG)患者和116例(AGB)患者接受了向RYGB的转换,SG患者最常见的转换原因是胃食管反流病(GERD,57.1%),而AGB患者是体重反弹(77.6%)。转换前平均BMI,SG组为36.7kg/m²,AGB组为43.8kg/m²。平均转换时间(月),SG组为52.9个月,AGB组为94.7个月。30天时并发症发生率,SG组为9.5%,AGB组为6%(p = 0.48);2年时,SG组为31%,AGB组为14.5%(p = 0.02)。1年时,因GERD/吞咽困难转换的患者中,转换后平均体重减轻百分比(%TWL),SG组为11.6%,AGB组为24.6%(p = 0.014);因体重相关原因转换的患者中,SG组为20.7% vs AGB组为27.6%(p = 0.027)。2年时总体平均%TWL,SG组为13.2%,AGB组为24.7%(p < 0.0035)。

结论

转换为RYGB后,AGB患者比SG患者在短期和中期体重减轻效果更好,即使考虑转换指征也是如此。从SG转换为RYGB对反流性疾病的缓解效果更佳。

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