Mabuchi Sayaka, Ohta Ryuichi, Egawa Keiko, Narai Yoko, Sano Chiaki
Clinical Education and Research Center, Shimane Prefectural Central Hospital, Izumo, JPN.
Community Care, Unnan City Hospital, Unnan, Shimane, JPN.
Cureus. 2022 May 14;14(5):e24990. doi: 10.7759/cureus.24990. eCollection 2022 May.
Granulomatous mastitis is a rare benign disease that typically occurs in parous women. Some reports have described cases of erythema nodosum appearing following granulomatous mastitis, which is often treated with steroids. Here, we report a case of granulomatous mastitis with erythema nodosum successfully treated via drainage only, which may have been caused by the higher plasma cortisol levels observed during pregnancy. Although mastitis is rare during pregnancy, the current case suggests that granulomatous mastitis should be considered in pregnant women with treatment-resistant mastitis, especially in those with erythema nodosum and a history of birth. Furthermore, patients with granulomatous mastitis may not require prednisolone treatment during pregnancy, which may help in preventing steroid-associated conditions such as infections and gestational diabetes mellitus.
肉芽肿性乳腺炎是一种罕见的良性疾病,通常发生在经产妇中。一些报告描述了肉芽肿性乳腺炎后出现结节性红斑的病例,这类病例常采用类固醇治疗。在此,我们报告一例仅通过引流成功治疗的伴有结节性红斑的肉芽肿性乳腺炎病例,其病因可能是孕期观察到的较高血浆皮质醇水平。尽管孕期乳腺炎罕见,但本例提示,对于患有难治性乳腺炎的孕妇,尤其是伴有结节性红斑和生育史的孕妇,应考虑肉芽肿性乳腺炎。此外,肉芽肿性乳腺炎患者在孕期可能不需要泼尼松龙治疗,这可能有助于预防如感染和妊娠期糖尿病等与类固醇相关的疾病。