Adams D H, Hubscher S G, Scott D G
Department of Medicine, Queen Elizabeth Hospital, Edgbaston, Birmingham, UK.
Postgrad Med J. 1987 Jul;63(741):581-2. doi: 10.1136/pgmj.63.741.581.
Granulomatous mastitis is a recently described, rare condition of unknown aetiology. It occurs in young, parous women as a tender extra-areolar breast lump and therefore needs to be differentiated from carcinoma. Histologically, a discrete granulomatous lobulitis is seen and because of morphological similarities to granulomatous thyroiditis it has been suggested it may be immunologically mediated. We present a patient in whom granulomatous mastitis presented with periarthritis and erythema nodosum, an association not previously described.
肉芽肿性乳腺炎是一种最近才被描述的、病因不明的罕见疾病。它发生在年轻的经产妇身上,表现为乳晕外触痛性乳房肿块,因此需要与癌进行鉴别。组织学上可见离散性肉芽肿性小叶炎,由于其形态与肉芽肿性甲状腺炎相似,有人提出它可能是由免疫介导的。我们报告一例肉芽肿性乳腺炎伴有周围关节炎和结节性红斑的患者,这种关联此前未见报道。