Bavikati Venkata Naidu, Muhameed Abdul Rasheed, Mohaley Nikitha, Thimmaiah Manjula K, Botlagunta Keerthi Kavya, Basalingappa Sangamesh
Department of Orthodontics, AME's Dental College & Hospital, Raichur, Karnataka, India.
Med Pharm Rep. 2022 Jan;95(1):65-70. doi: 10.15386/mpr-1911. Epub 2022 Jan 31.
Various procedures are available today to enhance tooth movement, with relative success rates, one among them being micro osteo-perforation (MOP). Our aim is to assess the rate of tooth movement and interleukin-1β levels in gingival crevicular fluid levels (GCF) after MOPs.
A group of 22 patients were selected, who required first premolars extraction and were designated for the split mouth study with equal allocation. MOP was performed on the right side, three vertical MOPs were given using 1.2 X 8 mm mini implants with the gap of 2 mm between them and surgical depth of the implant insertion was 5 mm. The left side was used as control. The individual canine retraction was initiated with placement of 150 grams on 19*25 SS wire. The case was evaluated at different timelines for canine retraction and interleukin-1β levels.
There was a significant difference in the rate of canine movement at 45 days (1.42 mm) and end of canine retraction on experimental side (2.61 mm). The GCF levels were raised at T1 and T2 intervals on the side of MOP and were statically significant (p=0.00).
MOP is a minimally invasive procedure which accelerates the tooth movement by 20%. The increase in IL-1β levels indicates a higher rate of chemical interaction on the surgically assisted side. For enhanced efficiency MOPs should be repeated every 6-8 weeks.
如今有多种方法可用于促进牙齿移动，且各有相应的成功率，其中之一是微骨穿孔术（MOP）。我们的目的是评估微骨穿孔术后牙齿移动的速率以及龈沟液（GCF）中白细胞介素-1β的水平。
选取22例需要拔除第一前磨牙的患者，进行双侧对照研究，随机分配。在右侧进行微骨穿孔术，使用1.2×8毫米的微型种植体进行三个垂直微骨穿孔，种植体之间的间隙为2毫米，种植体插入的手术深度为5毫米。左侧作为对照。通过在19×25不锈钢丝上施加150克的力开始个别尖牙的内收。在不同时间点评估尖牙内收情况和白细胞介素-1β水平。
在45天时实验侧尖牙移动速率（1.42毫米）和尖牙内收结束时（2.61毫米）与对照侧有显著差异。微骨穿孔侧在T1和T2时间段龈沟液水平升高，具有统计学意义（p = 0.00）。
微骨穿孔术是一种微创手术，可使牙齿移动速度加快20%。白细胞介素-1β水平的升高表明手术辅助侧有更高的化学相互作用速率。为提高效率，微骨穿孔术应每6 - 8周重复进行一次。
